Browse our latest Physics of Living Systems articles

Page 31 of 54
    1. Neuroscience
    2. Physics of Living Systems

    Binocular rivalry reveals an out-of-equilibrium neural dynamics suited for decision-making

    Robin Cao, Alexander Pastukhov ... Jochen Braun
    The statistics of binocular rivalry at different combinations of image contrast is reproduced quantitatively by competing out-of-equilibrium populations of independent neural assemblies with idealized attractor dynamics.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Price equation captures the role of drug interactions and collateral effects in the evolution of multidrug resistance

    Erida Gjini, Kevin B Wood
    A simple mathematical model reveals that antibiotic interactions and collateral effects of evolution are inseparable drivers of multidrug resistance linked by the well-known Price equation from evolutionary theory.
    1. Physics of Living Systems

    Effect of malaria parasite shape on its alignment at erythrocyte membrane

    Anil K Dasanna, Sebastian Hillringhaus ... Dmitry A Fedosov
    A numerical model of malaria parasite adhesion to an erythrocyte shows that the original egg-like shape of merozoites is more robust than other shapes in negotiating various physiological conditions during the alignment process upon erythrocyte invasion.
    1. Cancer Biology
    2. Physics of Living Systems

    Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization

    Joshua D Greenlee, Maria Lopez-Cavestany ... Michael R King
    Oxaliplatin-resistant colorectal cancer cells exhibit unregulated death receptor 4 expression with increased receptor palmitoylation and translocation into lipid rafts, increasing their sensitivity to apoptosis via TRAIL.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Calponin-homology domain mediated bending of membrane-associated actin filaments

    Saravanan Palani, Sayantika Ghosh ... Darius Vasco Köster
    Combination of actin and curly on lipid membranes constitutes a new, minimalistic system to generate high curvature actin rings that can contract upon the action of myosin II filaments.
    1. Physics of Living Systems

    Propelling and perturbing appendages together facilitate strenuous ground self-righting

    Ratan Othayoth, Chen Li
    Animals can, and robots should, use different types of appendages together to propel and perturb themselves to self-right when overturned, a strenuous yet crucial locomotor task.
    1. Neuroscience
    2. Physics of Living Systems

    The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores

    Zhenyong Wu, Nadiv Dharan ... Erdem Karatekin
    During neurotransmitter release, calcium-induced membrane insertion of the C2B domain of Synaptotagmin re-orients the bound SNARE complex which dilates the fusion pore in a mechanical lever action.
    1. Physics of Living Systems

    Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila

    Myron Barber Child VI, Jack R Bateman ... Hernan G Garcia
    Biophysical modeling and quantitative live-cell imaging converge to show that the century-old puzzle of somatic homolog pairing in Drosophila operates via a button model.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Crash landing of Vibrio cholerae by MSHA pili-assisted braking and anchoring in a viscoelastic environment

    Wenchao Zhang, Mei Luo ... Kun Zhao
    Mannose-sensitive hemagglutinin pili act as a braking and anchoring machine during the three-phase landing process of Vibrio cholerae.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Myosin-based regulation of twitch and tetanic contractions in mammalian skeletal muscle

    Cameron Hill, Elisabetta Brunello ... Malcolm Irving
    The physiological contraction of skeletal muscle is controlled by structural changes in the thick filaments, establishing a new paradigm for developing potential treatments for muscle weakness.