The statistics of binocular rivalry at different combinations of image contrast is reproduced quantitatively by competing out-of-equilibrium populations of independent neural assemblies with idealized attractor dynamics.
A simple mathematical model reveals that antibiotic interactions and collateral effects of evolution are inseparable drivers of multidrug resistance linked by the well-known Price equation from evolutionary theory.
Anil K Dasanna, Sebastian Hillringhaus ... Dmitry A Fedosov
A numerical model of malaria parasite adhesion to an erythrocyte shows that the original egg-like shape of merozoites is more robust than other shapes in negotiating various physiological conditions during the alignment process upon erythrocyte invasion.
Joshua D Greenlee, Maria Lopez-Cavestany ... Michael R King
Oxaliplatin-resistant colorectal cancer cells exhibit unregulated death receptor 4 expression with increased receptor palmitoylation and translocation into lipid rafts, increasing their sensitivity to apoptosis via TRAIL.
Saravanan Palani, Sayantika Ghosh ... Darius Vasco Köster
Combination of actin and curly on lipid membranes constitutes a new, minimalistic system to generate high curvature actin rings that can contract upon the action of myosin II filaments.
Animals can, and robots should, use different types of appendages together to propel and perturb themselves to self-right when overturned, a strenuous yet crucial locomotor task.
During neurotransmitter release, calcium-induced membrane insertion of the C2B domain of Synaptotagmin re-orients the bound SNARE complex which dilates the fusion pore in a mechanical lever action.
Myron Barber Child VI, Jack R Bateman ... Hernan G Garcia
Biophysical modeling and quantitative live-cell imaging converge to show that the century-old puzzle of somatic homolog pairing in Drosophila operates via a button model.
Cameron Hill, Elisabetta Brunello ... Malcolm Irving
The physiological contraction of skeletal muscle is controlled by structural changes in the thick filaments, establishing a new paradigm for developing potential treatments for muscle weakness.