Browse our latest Physics of Living Systems articles

Page 51 of 59
    1. Cell Biology
    2. Physics of Living Systems

    Spatiotemporal organization of branched microtubule networks

    Akanksha Thawani, Howard A Stone ... Sabine Petry
    A sequential reaction pathway involving TPX2, augmin and γ-TuRC governs the assembly and architecture of branched microtubule networks.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Imaging single-cell blood flow in the smallest to largest vessels in the living retina

    Aby Joseph, Andres Guevara-Torres, Jesse Schallek
    By using a specialized camera that corrects for eye blur, millions of single-blood-cells are imaged, and their speed measured, as they travel through the largest-to-smallest vessels of the retina.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Influenza A virus surface proteins are organized to help penetrate host mucus

    Michael D Vahey, Daniel A Fletcher
    By distributing receptor-binding and receptor-destroying proteins asymmetrically on their surface, filamentous influenza A virus particles create a Brownian ratchet that facilitates their passage through mucus.
    1. Physics of Living Systems

    Spatial control of irreversible protein aggregation

    Christoph Weber, Thomas Michaels, L Mahadevan
    A theoretical basis for the spatial regulation of protein aggregation shows how aggregates can partition preferentially into intracellular liquid compartments.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Environmental heterogeneity can tip the population genetics of range expansions

    Matti Gralka, Oskar Hallatschek
    Environmental heterogeneity can dramatically reduce the efficacy of selection and alter the neutral evolutionary dynamics in microbial range expansions.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Mechanics and dynamics of translocating MreB filaments on curved membranes

    Felix Wong, Ethan C Garner, Ariel Amir
    Principal curvature-dependent motion of bacterial actin MreB results in localization consistent with all known literature.
    1. Physics of Living Systems

    A multiphase theory for spreading microbial swarms and films

    Siddarth Srinivasan, C Nadir Kaplan, L Mahadevan
    A multiphase hydrodynamic theory reveals that the dynamics of colony expansion in microbial swarms and biofilms are limited by the constraints of water and nutrient availability.
    1. Physics of Living Systems

    Biophysics: Common concepts for bacterial collectives

    Hannah Jeckel, Noémie Matthey, Knut Drescher
    The expansion of bacterial swarms and the spreading of biofilms can be described by a unified biophysical theory that involves both active and passive processes.
    Version of Record
    Insight
    1. Immunology and Inflammation
    2. Physics of Living Systems

    Light-based tuning of ligand half-life supports kinetic proofreading model of T cell signaling

    Doug K Tischer, Orion David Weiner
    Direct control of ligand binding half-life with light shows that lifetime strongly affects T cell signaling.
    1. Developmental Biology
    2. Physics of Living Systems

    Cerebellar folding is initiated by mechanical constraints on a fluid-like layer without a cellular pre-pattern

    Andrew K Lawton, Tyler Engstrom ... Alexandra L Joyner
    A multi-phase wrinkling model accounts for the radial and circumferential tension and differential expansion between a uniformly proliferating outer fluid-like layer and an incompressible core that together drive cerebellar folding.