Browse our latest Stem Cells and Regenerative Medicine articles

A genetically diverse panel of subject-specific induced pluripotent stem cells models the in vitro susceptibility of cardiac cells to develop a cardiotoxic drug response.

Microtubule-depolymerizing kinesin, Klp10A, prevents overgrowth of the mother centrosome to prevent undesirable asymmetries during asymmetric divisions of Drosophila male germline stem cells.

A motor protein called Klp10A ensures that germline stem cells in male fruit flies divide to produce two sibling cells that are equal in size.

Building on previous work (Rodrigo Albors et al., 2015), we assess the contribution of individual cellular mechanisms in the context of spinal cord regeneration in the axolotl.

Ablation of canonical TGFβ signaling in muscle stem cells at any age is detrimental, and not beneficial, to effective skeletal muscle regeneration due to the promotion of premature fate commitment at the expense of progenitor amplification.

Identification of Hematopoietic stem cells (HSCs) in the genetically amenable organism Drosophila melanogaster paves the path to address HSC biology, both in normal and pathophysiological conditions.

Two methyl-binding domain proteins have interdependent functions in embryonic stem cells, and this interdependency extends to the DNA methylation/hydroxymethylation machinery.

The conserved mechanism of Notch down-regulation by endo-lysosomal trafficking plays important roles in the proliferation and differentiation of stem and progenitor cells during embryogenesis or organogenesis in vertebrates.

Analyzing the readout of Notch signaling with single RNA precision reveals that active transcription sites are the most accurate measure of Notch-dependent transcriptional activation.

Building on previous work (Dye et al., 2015) showing that pluripotent stem cell derived lung organoids were immature/fetal, the current study shows that in vivo transplantation leads to mature tissue, reminiscent of adult airways.