Browse our latest Stem Cells and Regenerative Medicine articles

A non-apoptotic function of the caspase Dronc is essential to promote tissue repair in response to necrosis via a previously uncharacterized mechanism.

It is safe to transplant autologous P63+ progenitor cells isolated from healthy bronchi to IPF patients for the treatment of IPF, and preliminary efficacy has been demonstrated in some patients.

Proteomic analyses reveal a distinct protein signature underlying microtubule organization and regenerative asymmetries in sensory neuron axons, supported by an in vitro system replicating key features of sensory neuron biology.

The chromatin-bound proteome of embryonic stem cells transitioning to 2C-like cells uncovers chromatin regulators involved in heterochromatin formation.

IL-6 signaling drives fibroblast activation in tendinopathy, emerging as a promising therapeutic target for these increasingly prevalent and costly tendon conditions.

Nicotine affects intestinal stem cells rather than Paneth cells, resulting in the increased stemness and tumorigenicity of intestinal stem cells.

A new example of niche formation, revealing the mode of niche cell migration, implicates extrinsic sources of positional information, and uncovers the pathway required for stereotypical positioning of the niche.

Downregulation of PTBP1 in neurons, but not astrocytes, alleviates motor symptoms in a Parkinson’s disease mouse model by inducing dopaminergic marker expression in striatal neurons and increasing striatal dopamine levels.