Fireflies that gather in swarms synchronize their flashing with rhythmic periodicity and provide insights into a new mechanism for the emergence of synchrony and periodicity.
The review proposes a novel mechanistic distinction between first- and second-order traveling waves that subserves a same canonical computation by ordering neuronal processing to impose a computational syntax.
A key finding is that MCAK binds to the proximal region of GTP cap where GDP‧Pi-tubulins accumulate, in addition to curved protofilaments at the distalmost tip.
The path of potassium through an ATP-dependent membrane pump is elucidated with a high-resolution structure within a lipid bilayer together with mutational analysis at key points along this pathway.
Rahul K Suryawanshi, Priyadarshini Jaishankar ... James S Fraser
The development of new small molecules demonstrates how pharmacologic inhibition of the coronavirus macrodomain restores innate immunity, leading to reduced viral replication and improved outcomes in severe infection.
Rebecca Garrett Jaszczak, Jay W Zussman ... Diana J Laird
A temporal and positional atlas of mouse primordial germ cell (PGC) migration reveals dynamic gene expression and somatic cell interactions that suggest how changing migratory niches regulate PGC development.
