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A novel targeted protein degradation system to achieve cell-type-specific enhancement of Wnt signaling.

Facultative parthenogenesis in whiptail lizards produces genome-wide homozygosity in offspring.

Strategic pegRNA designs and other approaches mitigating 5' and 3' interactions within pegRNAs can often lead to substantial improvements in prime editing efficiency.

Preparatory states within the motor cortex play a critical role in selecting an appropriate action in response to sensory input, dependent on the context.

Two atypical cadherins regulate organ growth by tuning the coupling of cell cycle duration to organ size.

Biosensor data collected by digital insoles is comparable to lab-based clinical assessments and can be used to identify subject-specific gait patterns.

A combined theoretical and experimental study revealed the mechanistic and structural basis of mutational effects on allostery and provided insights into the intrinsic connection of intra- and inter-domain properties.