Browse our latest research

Page 3 of 1,757
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Pan-tissue Transcriptome Analysis Reveals Sex-dimorphic Human Aging

    Siqi Wang, Danyue Dong ... Zefeng Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Developmental Biology

    Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation

    Shuo Chen, Jinxiu Liang ... Peidong Han
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    The molecular infrastructure of glutamatergic synapses in the mammalian forebrain

    Julia Peukes, Charlie Lovatt ... René A Frank
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Stem Cells and Regenerative Medicine

    CRISPR-edited DPSCs constitutively expressing BDNF enhance dentin regeneration in injured teeth

    Ji Hyun Kim, Muhammad Irfan ... Seung Chung
    Brain-derived neurotrophic factor/tropomyosin receptor kinase B signaling in promoting the differentiation and dentin-repair capacity of dental stem cells under inflammatory conditions offers a potential clinical strategy for repairing damaged teeth.
    1. Evolutionary Biology
    2. Structural Biology and Molecular Biophysics

    Prebiotic gas flow environment enables isothermal nucleic acid replication

    Philipp Schwintek, Emre Eren ... Dieter Braun
    Exponential nucleic acid replication can occur isothermally in a prebiotically plausible setting that accumulates and simultaneously separates the strands of nucleic acids through evaporation-driven flows at the gas–water interface.
    1. Microbiology and Infectious Disease

    Fast evolution of SOS-independent multi-drug resistance in bacteria

    Le Zhang, Yunpeng Guan ... Dayong Jin
    A single β-lactam exposure rapidly drives stable multidrug resistance in RecA-deficient bacteria through an SOS-independent mechanism involving oxidative stress-induced mutagenesis and antibiotic-driven selection.
    1. Neuroscience

    Molecular characterization of gustatory second-order neurons reveals integrative mechanisms of gustatory and metabolic information

    Rubén Mollá-Albaladejo, Manuel Jiménez-Caballero, Juan Antonio Sanchez-Alcaniz
    Leucokinin neurons integrate sweet and bitter taste inputs with starvation signals to regulate feeding initiation, balancing nutrient intake against the risk of toxin ingestion.
    1. Neuroscience

    A temporally restricted function of the dopamine receptor Dop1R2 during memory formation

    Jenifer C Kaldun, Emanuele Calia ... Simon G Sprecher
    The dopamine receptor Dop1R2 plays a crucial role in the formation of longer-lasting memories, while it is dispensable for short-term memories.
    1. Microbiology and Infectious Disease

    An abundant merozoite surface protein of Plasmodium falciparum modulates susceptibility to inhibitory antibodies

    Isabelle G Henshall, Jill Chmielewski ... Danny W Wilson
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience
    2. Computational and Systems Biology

    Reorganization of spinal neural connectivity following recovery after thoracic spinal cord injury: insights from computational modelling

    Natalia A Shevtsova, Andrew B Lockhart ... Simon M Danner
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing