In mammals, the vesicular glutamate transporter 1 acquired a proline-rich sequence that negatively regulates the spontaneous release of glutamate by reducing the exchange of synaptic vesicles along the axon.
A neuronal specific function of the mitochondrial chaperone, hTim8a in Complex IV biology provides insight into the pathomechanisms underlying the mitochondrial disease, Mohr-Tranebjaerg syndrome.
The MASK family of proteins regulate the action of the YAP/TAZ family of transcriptional coactivators, key regulators of stem cell proliferation and cancer.
A novel live-cell mRNA imaging technology identifies individual living cells based on their gene expression and enables the concurrent study of their physiology.
The brain continuously updates the learned temporal relationship between motor commands and their associated somatosensory feedback, which determines the perceived intensity and ticklishness of self-touch.
