Genetic lineage tracing and live-cell imaging demonstrate that NeuroD1 does not convert microglia into neurons but instead promotes microglial apoptosis, challenging claims of in situ glia-to-neuron conversion.
Adhithi R Raghavan, Kieron May ... Andreas Hochwagen
Meiotic axis protein deposition and double-strand break formation near yeast chromosome ends are regulated by multiple distinct layers of regulation, including the chromatin modifiers Sir2/3 and Dot1.
Specialized anterior intestinal cells in Caenorhabditis elegans act as sentinels, regulating pathogen responses and linking food availability to gut peptide secretion through pyruvate metabolism.
Carrying 'teaching' signals and modulating movement, two highly conserved functions of the dopaminergic system across all animals, are brought about by the same individual dopaminergic neurons in an insect larva.
