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Gluconeogenesis rescues insects from glycogen phosphorylase suppression, establishing metabolic redundancy as a key consideration for insecticide target selection.

Allosteric transition between two disulfide configurations of NK cell receptor KIR2DL4 is a functional switch that controls receptor residence at the cell surface for binding and internalization of soluble HLA-G.

Multi-omics investigation identifies cell-type JAK-STAT heterogeneity as a predictive biomarker for PD-1 blockade in breast cancer.

A saw-like proboscis, forceful pulling movements, and precise targeting of softer skin sites allow tsetse flies to draw blood from remarkably diverse vertebrate hosts.

Passive recordings miss patterns of brain activity that fade before they can be observed, but perturbations designed to re-excite those patterns make estimates of neural connections far more accurate.

Systematic dissection of Rab GTPase function in developing neurons reveals that early and recycling endosome-associated Rabs regulate largely distinct aspects of neuronal morphogenesis and circuit assembly across developmental time.

Computational and theoretical analyses reveal that Caenorhabditis elegans whole-brain activity can be represented in an 8-dimensional hyperbolic manifold that hierarchically links sensory ON/OFF inputs to motor states, providing a compact geometric framework for how a nervous system processes sensory information.