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    1. Neuroscience

    Esr1-dependent signaling and transcriptional maturation in the medial preoptic area of the hypothalamus shape the development of mating behavior during adolescence

    Koichi Hashikawa, Yoshiko Hashikawa ... Garret D Stuber
    Esr1 directs adolescent transcriptional maturation of medial preoptic GABAergic neurons, enabling the normal development of mating behavior in male and female mice.
    1. Neuroscience

    Material damage to multielectrode arrays after electrolytic lesioning is insignificant

    Alice Tor, Stephen E Clarke ... Paul Nuyujukian
    An analysis of the largest publicly available collection of scanning electron microscopy images of explanted multielectrode arrays reveals that electrolytic lesioning causes no significant additional damage to array electrodes.
    1. Neuroscience

    Tunable Bessel beam two-photon fluorescence microscopy for high-speed volumetric imaging of brain dynamics

    Mengyang Jacky Li, Jinghui Wang ... Tian-Ming Fu
    Tunable Bessel beam two-photon fluorescence microscopy enables high-speed volumetric intravital imaging of subcellular dynamics within living mouse brains with fully tunable spatial resolution and volume coverage, allowing flexible sampling and measurements of vascular, neuronal, and immune dynamics.
    1. Neuroscience

    Synaptotagmin isoforms differentially regulate glutamate and GABA release in the lateral habenula

    Dustin N White, J Keenan Kushner ... Michael HB Stowell
    Not revised
    Reviewed Preprint v1
    • Useful
    • Inadequate
    1. Neuroscience

    Fragile polyQ assemblies cause Golgipathy in Huntington’s disease

    Lixiang Ma, Xinyu Chen ... Hexige Saiyin
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Immunology and Inflammation

    Simplifying principles that underlie the highly complex peptide motif of the promiscuous chicken class I molecule, BF2*21:01

    Michael Harrison, Paul E Chappell ... Jim Kaufman
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Celldetective: an AI-enhanced image analysis tool for unraveling dynamic cell interactions

    Rémy Torro, Beatriz Díaz-Bello ... Laurent Limozin
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Virus specific impacts on honey bee flight performance are mediated by the octopamine pathway

    Naomi G Kaku, Michelle L Flenniken
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Genetics and Genomics

    The cistrome response to hypoxia in human umbilical vein endothelial cells

    Ayush Singh, Viktor Pastukh ... Hank W Bass
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Evolutionary Biology

    Species biology and demographic history determine species vulnerability to climate change in tropical island endemic birds

    Ratnesh Karjee, Vikram Iyer ... Balaji Chattopadhyay
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Inadequate
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