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    1. Microbiology and Infectious Disease

    A network perspective on the role of c-di-GMP-associated protein complexes in biofilm formation

    Marie-Francoise Noirot-Gros, Peter Larsen ... Philippe Noirot
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease
    2. Epidemiology and Global Health

    The age and sex dynamics of heterosexual HIV transmission in Zambia: an HPTN 071 (PopART) phylogenetic and modelling study

    Matthew Hall, William Probert ... the HPTN 071 (PopART) study team
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Verbal versus Nonverbal Processing Leads to Generalized Hemispheric Laterality Effects that Span Multiple Networks

    Wendy Sun, Lauren M DiNicola, Randy L Buckner
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Comparative multi-omics of the macrophage response to infection with Mycobacterium tuberculosis complex bacteria reveals pathogen-driven epigenomic reprogramming

    Thomas J Hall, Morgane Mitermite ... David E MacHugh
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Sex differences in exploration–exploitation strategies during home-cage decision making

    Chantelle L Murrell, Alex A Legaria ... Alexxai V Kravitz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Decoupling AMPK from fatty acid synthesis allows maintenance of fitness late in life

    Hanane Hadj-Moussa, Megan Ulusan ... Jonathan Houseley
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Medicine

    Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach

    Jacky Guy, Elena Hein ... Adrian Bird
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    PXGS: a Poly-Transgene Expression System based on Mutually Exclusive Splicing of Dscam

    Renee Yin Yu, Alyeri Bucio-Méndez, Brian E Chen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Convincing
    1. Structural Biology and Molecular Biophysics

    In silico design and validation of high-affinity RNA aptamers for SARS-CoV-2 comparable to neutralizing antibodies

    Yanqing Yang, Lulu Qiao ... Ruhong Zhou
    Computer-Aided Aptamer Modeling and Optimization (CAAMO) enables structure-guided RNA aptamer affinity maturation, producing a SARS-CoV-2 RBD (receptor binding domain) binder that rivals neutralizing antibodies and retains predicted activity across variants.
    1. Neuroscience

    The Crunchometer, a low-cost, open-source acoustic analysis of feeding microstructure

    Elvi Gil Lievana, Benjamin Arroyo ... Ranier Gutierrez
    Making the moment-to-moment dynamics of solid-food intake measurable in any laboratory enables researchers to map the brain circuits that control appetite and accelerate the development of treatments for obesity.
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