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Fixation-pattern similarity analysis reveals adaptive changes in face-viewing strategies following aversive learning
Lea Kampermann et al.
A novel approach based on eye-movement patterns reveals adaptive changes during viewing of faces and fear generalization.
Structural Biology and Molecular Biophysics
Inducing conformational preference of the membrane protein transporter EmrE through conservative mutations
Maureen Leninger et al.
Conservative mutations within a secondary active transport protein influenced the conformational equilibrium probed using NMR spectroscopy which correlated to the functional output in vivo.
Human Biology and Medicine
Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape
Chen Farhy et al.
Biochemistry and Chemical Biology
Deamidation disrupts native and transient contacts to weaken the interaction between UBC13 and RING-finger E3 ligases
Priyesh Mohanty et al.
neurons have functional dendritic spines
Andrea Cuentas-Condori et al.
has bona fide dendritic spines, suggesting that the advantages of small model organisms, such as genetic manipulations and live-cell imaging, can be exploited to study dendritic spines.
Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress
Abigail Buchwalter et al.
Emerin, a protein that plays key roles in nuclear organization, can be dynamically degraded in response to environmental stimuli such as ER stress.
A neural mechanism for contextualizing fragmented inputs during naturalistic vision
Daniel Kaiser et al.
In scene-selective occipital cortex and within 200 ms of processing, visual inputs are sorted according to their typical spatial position within a scene.
TORC2-Gad8-dependent myosin phosphorylation modulates regulation by calcium
Karen Baker et al.
IQ domain phosphorylation regulates calmodulin binding and myosin-1 function.
Immunology and Inflammation
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis
Carolyn M Walsh et al.
Microbiology and Infectious Disease
Genetically diverse uropathogenic
adopt a common transcriptional program in patients with UTIs
Anna Sintsova et al.
Conserved transcriptomic profile of uropathogenic
in patients identifies an infection-specific metabolic state.
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