Targeted computational redesign of an IL-7 superkine with enhanced folding efficiency and receptor affinity demonstrates superior immune-stimulatory and antitumor activity over wild-type IL-7.
The glial-specific role of betaPix during cerebral blood vessel development has been revealed by establishing a new betaPix conditional trap allele in zebrafish.
A simple statistical model captures the essential features of object motion in a large database of natural scenes, helping to shed light on the challenges posed to sensory and motor systems.
Genetic approaches identify Rtf1-dependent transcriptional pausing as an essential mechanism governing the deployment of the cardiac gene program during myocardial differentiation from the mesoderm.
