Browse our latest research

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    1. Structural Biology and Molecular Biophysics

    Conformational Changes of the ABC Transporter BmrA Depend on Membrane Curvature

    Alicia Damm, Kemil Belhadji ... Patricia Bassereau
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    • Convincing
    1. Developmental Biology

    Genetic Network Shaping Kenyon Cell Identity and Function in Drosophila Mushroom Bodies

    Pei-Chi Chung, Kai-Yuan Ku ... Hung-Hsiang Yu
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Immunology and Inflammation

    Single-cell transcriptomics identifies altered neutrophil dynamics and accentuated T-cell cytotoxicity in tobacco-flavored e-cigarette-exposed mouse lungs

    Gagandeep Kaur, Thomas Lamb ... Irfan Rahman
    Profiling cell-specific immune responses reveals altered neutrophil function and enhanced T-cell mediated cell death following acute in vivo exposure to tobacco-flavored e-cigarette aerosol using single-cell technology.
    1. Biochemistry and Chemical Biology

    Gut microbe-derived trimethylamine shapes circadian rhythms through the host receptor TAAR5

    Kala K Mahen, William J Massey ... Jonathan Mark Brown
    The gut microbe-derived metabolite trimethylamine (TMA) activates the host receptor trace amine-associated 5 (TAAR5) to instruct circadian rhythms.
    1. Physics of Living Systems

    Feeding rates in sessile versus motile ciliates are hydrodynamically equivalent

    Jingyi Liu, Yi Man ... Eva Kanso
    Fluid flow analysis reveals that both swimming and sessile ciliates achieve competitive nutrient uptake, resolving the long-standing debate over the hydrodynamic advantage of either strategy.
    1. Evolutionary Biology

    Accelerated evolution in networked metapopulations of Pseudomonas aeruginosa

    Partha Pratim Chakraborty, Rees Kassen
    Centralized migration accelerates adaptation and drives parallel evolution, emphasizing the key influence of spatial organization on evolutionary dynamics across systems from pathogen transmission to species range shifts.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during mouse skeletal muscle regeneration

    Yue Lu, Tezin Walji ... Elizabeth H Chen
    Branched actin cytoskeleton is critical for myoblast fusion during mouse skeletal muscle regeneration.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Cancer Biology
    2. Cell Biology

    Mitochondrial protein carboxyl-terminal alanine-threonine tailing promotes human glioblastoma growth by regulating mitochondrial function

    Bei Zhang, Ting Cai ... Zhihao Wu
    The carboxyl-terminal alanine-threonine-tailed protein ATP5α helps glioblastoma mitochondria maintain a high membrane potential and keep the permeability transition pore closed, thereby promoting tumor growth and increasing resistance to apoptosis.
    1. Neuroscience

    Human brain dynamics and spatiotemporal trajectories during threat processing

    Joyneel Misra, Luiz Pessoa
    Intrinsic neural attractors and extrinsic environmental inputs jointly steer the dynamic trajectories of brain activity during threat processing.
    1. Neuroscience

    Toward Robust Neuroanatomical Normative Models: Influence of Sample Size and Covariates Distributions

    Camille Elleaume, Bruno Hebling Vieira ... the Australian Imaging Biomarkers and Lifestyle flagship study of ageing
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing