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    1. Structural Biology and Molecular Biophysics

    Allosteric effects of the coupling cation in melibiose transporter MelB

    Parameswaran Hariharan, Yuqi Shi ... Lan Guan
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Glycolysis-dependent Sulfur Metabolism Orchestrates Morphological Plasticity and Virulence in Fungi

    Dhrumi Shah, Nikita Rewatkar ... Sriram Varahan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology
    2. Genetics and Genomics

    Single-cell transcriptomics of X-ray irradiated Drosophila wing discs reveals heterogeneity related to cell-cycle status and cell location

    Joyner Cruz, Willam Y Sun ... Iswar K Hariharan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Distinct goal location beta frequency dynamics in hippocampus and prefrontal cortex across learning

    Glingna Wang, Nan Zhou ... Jai Y Yu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    Non-visual light modulates behavioral memory and gene expression in C. elegans

    Zhijian Ji, Bingying Wang ... Dengke K Ma
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology

    Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damage

    Zhiwei Huang, Songhao Luo ... Jiajun Zhang
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Dual-feature selectivity enables bidirectional coding in visual cortical neurons

    Katrin Franke, Nikos Karantzas ... Andreas Tolias
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Microbiology and Infectious Disease

    Stratification of viral shedding patterns in saliva of COVID-19 patients

    Hyeongki Park, Yoshimura Raiki ... Taiga Miyazaki
    Distinct patterns of SARS-CoV-2 viral dynamics in saliva reveal heterogeneity that cannot be sufficiently explained by conventional clinical characteristics or microRNA profiles alone.
    1. Computational and Systems Biology

    Targeted computational design of an interleukin-7 superkine with enhanced folding efficiency and immunotherapeutic efficacy

    See-Khai Lim, Wen-Ching Lin ... Kurt Yun Mou
    Targeted computational redesign of an IL-7 superkine with enhanced folding efficiency and receptor affinity demonstrates superior immune-stimulatory and antitumor activity over wild-type IL-7.
    1. Developmental Biology

    Glial betaPix is essential for blood vessel development in the zebrafish brain

    Shihching Chiu, Qinchao Zhou ... Jing-Wei Xiong
    The glial-specific role of betaPix during cerebral blood vessel development has been revealed by establishing a new betaPix conditional trap allele in zebrafish.
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