Browse our latest research

Phospholipase Cβ3 is translocated and activated by the heterotrimeric G protein subunit Gα_q at the plasma membrane, but the Gβγ heterodimer is required for maximum activation.

Intracellular zinc dynamically changes during sperm capacitation and regulates Slo3-mediated hyperpolarization, while directly inhibiting Slo3 currents through residues contributing to its slow dissociation.

Bridging biophysical neuron models with tractable population dynamics opens a route to whole-brain investigation of ion-driven pathological states such as epilepsy and their potential therapeutic targets.

A generalizable computational approach automatically identifies individual common marmosets to serve as support for presenting and analyzing behavioral tasks without relying on extensive manual work.

Depression-specific symptoms blunt mood responses to unexpected outcomes, whereas anxiety-specific symptoms amplify them in non-clinical participants, with depression-related blunting also replicated in patients with affective disorders.

Apical PKD2L1 channels generate phasic and sustained currents that together make spinal cerebrospinal fluid-contacting neurons exquisite pH sensors.

Detailed, single-cell spatial gene expression across multiple gastruloids highlights macro-scale organizational consistency, simultaneous with variance in meso-scale patterning.