Browse our latest research

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    1. Immunology and Inflammation

    Cas9+ conditionally immortalized neutrophil progenitors as a tool for genome-wide CRISPR screening for neutrophil differentiation and function

    Robyn M Jong, Krystal L Ching ... Sarah A Stanley
    Cas9+ER-Hoxb8 neutrophils are a new tool for investigating neutrophil biology in vitro and in vivo.
    1. Cell Biology
    2. Neuroscience

    CO2-dependent opening of connexin 43 hemichannels

    Valentin Mihai Dospinsecu, Alexander Mascarenhas ... Nicholas Dale
    Connexin43 is the most ubiquitously expressed connexin in the human body, and the CO2-dependent opening of Connexin43 hemichannels implies that CO2 may influence many physiological processes.
    1. Developmental Biology

    HSD17B7 is required for the function of sensory hair cells by regulating cholesterol synthesis

    Yuqian Shen, Ziyang Wang ... Dong Liu
    HSD17B7-dependent cholesterol biosynthesis is essential for hair cell function, implicating HSD17B7 disruption in the pathogenesis of hearing loss.
    1. Cancer Biology
    2. Physics of Living Systems

    Heterotypic interfacial tension between oncogenic and wild-type populations forms the mechanical basis of tissue-specific oncogenesis in epithelia

    Amrapali Datta, Phanindra Dewan ... Medhavi Vishwakarma
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Modality-Specific and Amodal Language Processing by Single Neurons

    Yair Lakretz, Naama Friedmann ... Itzhak Fried
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Arousal modulates functional connectivity through structured and hemispherically asymmetric community architecture during wakefulness

    Xiangyu Kong, Siyu Li, Gaolang Gong
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Divergent spatiotemporal integration of whole-field visual motion in medaka and zebrafish larvae

    Yasuko Isoe, Yasmine Fatima Mabene ... Florian Engert
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Immunology and Inflammation

    TGF-β drives the conversion of conventional NK cells into uterine tissue-resident NK cells to support murine pregnancy

    Josselyn D Barahona, Liping Yang ... Wayne M Yokoyama
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Intron Retention Controls Localization of lncRNAs PURPL and MALAT1 to Promote Cell Proliferation and Migration

    Ioannis Grammatikakis, Chosita Norkaew ... Ashish Lal
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    • Compelling
    1. Cell Biology
    2. Physics of Living Systems

    The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch

    Robbert van der Pijl, Jochen Gohlke ... Coen Ottenheijm
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid