Browse our latest research

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    1. Neuroscience

    Prolonged oscillating preoptic area kisspeptin neuron activity underlies the preovulatory luteinizing hormone surge in mice

    Ziyue Zhou, Cheng-Yu Huang, Allan Edward Herbison
    High levels of circulating estradiol enable the RP3V kisspeptin neuron population to exhibit long-lasting synchronized oscillatory behavior that drives GnRH neurons to initiate the LH surge.
    1. Cell Biology
    2. Developmental Biology

    A novel 3D visualization method in mice identifies the periportal lamellar complex (PLC) as a key regulator of hepatic ductal and neuronal branching morphogenesis

    Tongtong Xu, Fujun Cao ... Chengjian Zhao
    A high-resolution 3D imaging platform reveals the periportal lamellar complex as a novel structural feature in the mouse liver, regulating bile duct and nerve migration during fibrosis.
    1. Stem Cells and Regenerative Medicine

    Endometrial epithelial cells with high ALDH activity control uterine development and regeneration

    Suni Tang, Anna Catherine Unser ... Diana Monsivais
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Use-dependent regulation of the axonal action potential in parvalbumin-expressing interneurons

    Sophie R Liebergall, Ethan M Goldberg
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    PKMζ-PKCι/λ double-knockout demonstrates atypical PKC is crucial for the persistence of hippocampal LTP and spatial memory

    Panayiotis Tsokas, Changchi Hsieh ... Todd Charlton Sacktor
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Metabolic basis of the astrocyte-synapse interaction governs dopaminergic-motor connection

    Yanru Xu, Piaoping Kong ... Zhiguo Ma
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Cancer Biology

    Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8

    Hyunkyung Kong, Jiyeon Choi ... Kevin M Brown
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology

    Junctional and Actomyosin Dynamics Drive Endothelial Cell Rearrangements during Vascular Tube Formation

    Ludovico Maggi, Jianmin Yin ... Heinz-Georg Belting
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Bilateral equalization of synaptic output in olfactory glomeruli of Xenopus tadpoles

    Marta Casas, Beatrice Terni, Artur Llobet
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cancer Biology

    Molecular architecture of the tumor microenvironment caused by BRCA1 and BRCA2 somatic mutations in lung adenocarcinoma

    Gaoming Liao, Xinbin Yang ... Gang Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid