Browse our latest research

Page 2 of 1,874
    1. Neuroscience

    Compensation of Hyperexcitability with Simulation-Based Inference

    Daniel Müller-Komorowska, Tomoki Fukai
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Developmental Biology

    SVEP1 enables efficient binding of Angiopoietin-2 to the TIE1 receptor, allowing receptor phosphorylation and downstream signaling

    Katharina Uphoff, Melina Hußmann ... Dörte Schulte-Ostermann
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Brief disruption of activity in a subset of dopaminergic neurons during consolidation impairs long-term memory by fragmenting sleep

    Lin Yan, Litao Wu ... Chang Liu
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Neuroscience

    Spine nanostructure profiling of cultured neurons from mouse models reveals a schizophrenia-linked role for Ecrg4

    Yutaro Kashiwagi, Qingrui Liu ... Shigeo Okabe
    Population-level analysis of dendritic spine nanostructure identifies distinct synaptic signatures of schizophrenia and autism, revealing Ecrg4 as a regulator of schizophrenia-associated spine pathology.
    1. Ecology

    Global relationships between body size and urban affinity across more than 30,000 plant and animal species

    Corey T Callaghan, Diana E Bowler ... Thomas Merckx
    Across the tree of life, urban communities are consistently characterized by many urban-avoiding species and few urban exploiters, revealing a general pattern in biodiversity responses to urbanization.
    1. Microbiology and Infectious Disease

    A dual role for PGLYRP1 in host defense and immune regulation during B. pertussis infection

    David M Rickert, Sasha Cardozo ... Ciaran Skerry
    Bordetella pertussis hijacks the host innate immune protein PGLYRP1 via tracheal cytotoxin to suppress inflammation and evade killing, revealing a novel immune evasion strategy.
    1. Neuroscience

    In vivo mapping of striatal neurodegeneration in Huntington’s disease with Soma and Neurite Density Imaging

    Vasileios Ioakeimidis, Marco Palombo ... Claudia Metzler-Baddeley
    Novel SANDI diffusion modelling reveals Huntington’s disease-related striatal abnormalities in proxy soma measures, explaining atrophy and motor impairment, and supporting SANDI indices as in vivo biomarkers of human neurodegenerative processes.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Divergent C. elegans toxin alleles are suppressed by distinct mechanisms

    Stefan Zdraljevic, Laura Walter-McNeill ... Leonid Kruglyak
    A maternal toxin-antidote element has degenerated into an antidote-only remnant in some Caenorhabditis elegans isolates, while in others, the toxin may instead be silenced by small RNAs.
    1. Cell Biology

    Pre-rRNA represses gene transcription in the XY body of male germ cells

    Linlin Chen, Xiaochen Gai ... Xiaochun Yu
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Evolutionary Biology

    Frequency dynamics predict viral fitness, antigenic relationships and epidemic growth

    Marlin D Figgins, Trevor Bedford
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete