Browse our latest research

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    1. Neuroscience

    Selective consolidation of learning and memory via recall-gated plasticity

    Jack Lindsey, Ashok Litwin-Kumar
    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    Structure and function of the ROR2 cysteine-rich domain in vertebrate noncanonical WNT5A signaling

    Samuel C Griffiths, Jia Tan ... Hsin-Yi Henry Ho
    Structure-function analysis of the ROR2 cysteine-rich domain reveals a new mechanism of WNT5A reception at the cell surface and provides new insights into the pathogenic mechanisms of Robinow syndrome-driving ROR2 mutations.
    1. Neuroscience

    Systemic pharmacological suppression of neural activity reverses learning impairment in a mouse model of Fragile X syndrome

    Amin MD Shakhawat, Jacqueline G Foltz ... Jennifer L Raymond
    The capacity for new cerebellum-dependent learning is influenced by the recent history of neural activity in a mouse model of Fragile X syndrome, suggesting a role for metaplasticity.
    1. Cell Biology
    2. Physics of Living Systems

    Neutrophils actively swell to potentiate rapid migration

    Tamas L Nagy, Evelyn Strickland, Orion D Weiner
    Actin-independent water influx complements actin-driven cytoskeletal forces to potentiate chemoattractant-induced migration in primary human neutrophils.
    1. Neuroscience

    Hippocampus and striatum show distinct contributions to longitudinal changes in value-based learning in middle childhood

    Johannes Falck, Lei Zhang ... Yee Lee Shing
    Longitudinal and computational analyses reveal an early and temporally stable hippocampal and striatal involvement in reinforcement learning in 6-to-7-year-old children.
    1. Immunology and Inflammation

    ER-to-lysosome Ca2+ refilling followed by K+ efflux-coupled store-operated Ca2+ entry in inflammasome activation and metabolic inflammation

    Hyereen Kang, Seong Woo Choi ... Myung-Shik Lee
    The role of lysosomal Ca2+ flux associated with K+ efflux, a well-known event in inflammasome activation in metabolic inflammation and inflammasome activation, has been presented.
    1. Neuroscience

    Atypical local and global biological motion perception in children with attention deficit hyperactivity disorder

    Junbin Tian, Fang Yang ... Li Yang
    Children with ADHD exhibit atypical biological motion perception, with local processing related to social interaction skills and global processing showing age-related improvement.
    1. Cell Biology
    2. Developmental Biology

    A CDK1 phosphorylation site on Drosophila PAR-3 regulates neuroblast polarisation and sensory organ formation

    Nicolas Loyer, Elizabeth KJ Hogg ... Jens Januschke
    PAR-3/Baz function is regulated by CDK1 in asymmetrically dividing cells in the central and peripheral nervous system of Drosophila revealing direct regulation of cell polarity by the cell cycle machinery in the context of cell fate specification.