Browse our latest research

Page 2 of 1,655
    1. Neuroscience

    A Novel Mouse Model for LAMA2-Related Muscular Dystrophy: Analysis of Molecular Pathogenesis and Clinical Phenotype

    Dandan Tan, Yidan Liu ... Hui Xiong
    Revised
    Reviewed Preprint v2 Updated
    1. Microbiology and Infectious Disease

    Regulative synthesis of capsular polysaccharides in the pathogenesis of Streptococcus suis

    Xingye Wang, Jie Wang ... Beinan Wang
    Not yet revised
    Reviewed Preprint v1
    1. Microbiology and Infectious Disease

    HIV-1 Vif disrupts phosphatase feedback regulation at the kinetochore, leading to a pronounced pseudo-metaphase arrest

    Dhaval A Ghone, Edward L Evans ... Aussie Suzuki
    Not yet revised
    Reviewed Preprint v1
    1. Cell Biology
    2. Computational and Systems Biology

    De novo-designed minibinders expand the synthetic biology sensing repertoire

    Zara Y Weinberg, Sarah S Soliman ... Hana El-Samad
    Revised
    Reviewed Preprint v2 Updated
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    PRR adjuvants restrain high stability peptides presentation on APCs

    Bin Li, Jin Zhang ... Chao Wu
    Adjuvants, MPLA and CpG especially, modulate the peptide repertoires presented on the surface of APCs, preferring the presentation of low-affinity exogenous peptides rather than high-affinity peptides.
    1. Cell Biology
    2. Neuroscience

    Rab11 suppresses neuronal stress signaling by localizing dual leucine zipper kinase to axon terminals for protein turnover

    Seung Mi Kim, Yaw Quagraine ... Jung Hwan Kim
    Coupling between subcellular localization and protein turnover of a neuronal stress kinase, DLK, and its role in neuronal stress responses in Drosophila.
    1. Cell Biology
    2. Neuroscience

    Neurons enhance blood–brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion

    Lu Yang, Zijin Lin ... Li Liu
    The established triple co-culture blood-–brain barrier (BBB) model could be used for predicting drugs’ BBB permeability, and co-culture with neurons and astrocytes enhanced brain endothelial cells’ integrity by secreting GDNF, which upregulated claudin-5 and VE-cadherin expression.
    1. Neuroscience

    PKCδ is an activator of neuronal mitochondrial metabolism that mediates the spacing effect on memory consolidation

    Typhaine Comyn, Thomas Preat ... Pierre-Yves Plaçais
    In neurons of the Drosophila brain’s memory center, PKCδ relays a post-learning dopamine signal to mitochondria, boosting their metabolic activity and thereby unlocking long-term memory formation.
    1. Neuroscience

    Transformation of valence signaling in a mouse striatopallidal circuit

    Donghyung Lee, Nathan Lau ... Cory M Root
    The representation of odor transforms from high dimensional, population level encoding of valence and identity in the OT, to a low dimensional representation of valence in the VP.
    1. Structural Biology and Molecular Biophysics

    Elucidating ATP’s role as solubilizer of biomolecular aggregate

    Susmita Sarkar, Saurabh Gupta ... Jagannath Mondal
    ATP prevents condensation of aggregation-prone intrinsically disordered protein by modulating its conformation.