A streamlined seven-component cell-free expression platform simplifies reaction design while maintaining high productivity and enabling robust synthesis of challenging proteins for diverse applications.
At moderate densities, small mammalian herbivores can enhance livestock weight gains by suppressing toxic plants and improving both the abundance and nutritional quality of palatable forage in rangelands.
Primordial cardiomyocytes play an essential role in myocardial morphogenesis and coronary vascularization, but not in adult zebrafish heart regeneration.
A genome-wide RNA interference screen identified cellular processes that modulate the phase separation of a TDP-43 mutant, providing a framework for dissecting the link between its phase behavior and disease-associated aggregation.
Nahir Guadalupe Gazal, Maria Jose Castellanos-Montiel ... Nicolás Unsain
An actin-nucleation-dependent assembly of the axonal membrane skeleton reveals that βII-spectrin gap-and-patch patterns in human motor neurons represent an intermediate stage of cytoskeletal maturation.
Layer 6b neurons shape state-dependent brain rhythms and responses to orexin, revealing an underappreciated cortical mechanism that may help explain disrupted sleep-wake regulation in neurodevelopmental and psychiatric disorders more broadly.
Single-cell observations refute the expectation that centrosome positioning is critical for epithelial cell polarization while showing that proper positioning enhances polarization efficiency.
