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Page 2 of 1,861
    1. Cell Biology
    2. Cancer Biology

    DuoHexaBody-CD37 induces direct cytotoxic signaling in diffuse large B-cell lymphoma

    Simar Pal Singh, Kumar Mangalam ... Annemiek B van Spriel
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Systematic characterisation of site-specific proline hydroxylation using hydrophilic interaction chromatography and mass spectrometry

    Hao Jiang, Jimena Druker ... Angus I Lamond
    A robust workflow for the identification of proline hydroxylation sites in proteins was established, using hydrophilic interaction chromatography enrichment and LC-MS/MS together with refining and filtering parameters during data analysis.
    1. Physics of Living Systems

    Controlling the synchronization and symmetry breaking of coupled bacterial pili on active biofilm carpets

    Baha Altın, Enes Talha Günay ... Askin Kocabas
    Active biofilm carpets generate Mexican-wave-like synchronized dynamics and topological defects through nonreciprocal pili interactions.
    1. Cell Biology

    PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progression

    Jimena Druker, Hao Jiang ... Angus I Lamond
    Proline hydroxylation of RepoMan (CDCA2) at P604 by PHD1 is shown to be important for mitotic progression and regulating interaction with PP2A regulatory subunit B56 gamma.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into the recruitment of viral type 2 IRES to ribosomal preinitiation complex for protein synthesis

    Deepakash Das, Tanweer Hussain
    The viral type 2 internal ribosome entry site uses a unique mechanism to hijack the host ribosomal machinery by interacting with initiator tRNA and 40S head.
    1. Neuroscience

    Intrinsic properties link a network model to zebra finch song

    Nelson D Medina, Dan Margoliash
    Whole-cell recordings paired with a network model show that post-inhibitory rebound excitation in premotor neurons couples intrinsic excitability to the temporal structure of learned birdsong.
    1. Microbiology and Infectious Disease

    Mycobacterium tuberculosis partitions the Krebs cycle under iron starvation

    Agnese Serafini, Acely Garza-Garcia ... Riccardo Manganelli
    Mycobacterium tuberculosis rewires central carbon metabolism to circumvent iron-dependent metabolic routes during iron starvation.
    1. Developmental Biology

    A cell atlas of the developing human outflow tract of the heart and its adult aortic valve derivatives

    Rotem Leshem, Syed Murtuza-Baker ... Nicoletta Bobola
    Transcriptomic profiling of the developing human outflow tract and adult aortic valves reveals that adult valve cells retain distinct embryonic molecular signatures.
    1. Neuroscience

    SynaptoTagMe, a toolkit for in vivo mapping and modulating neurotransmission at single-cell resolution

    Andrea Cuentas-Condori, Patricia Chanabá-López ... Daniel A Colón-Ramos
    Endogenous tagging and conditional silencing of vesicular transporters reveal widespread, conserved co-transmission, and enable causal dissection of transmitter-specific synaptic function, linking molecular identity to circuit dynamics and behavior in vivo.
    1. Neuroscience

    Hippocampal neuronal and astrocytic responses to noradrenaline and natural arousal

    Sian N Duss, Maria Wilhelm ... Peter Rupprecht
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid