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    1. Biochemistry and Chemical Biology

    Gut microbe-derived trimethylamine shapes circadian rhythms through the host receptor TAAR5

    Kala K Mahen, William J Massey ... Jonathan Mark Brown
    The gut microbe-derived metabolite trimethylamine (TMA) activates the host receptor trace amine-associated 5 (TAAR5) to instruct circadian rhythms.
    1. Evolutionary Biology

    Accelerated evolution in networked metapopulations of Pseudomonas aeruginosa

    Partha Pratim Chakraborty, Rees Kassen
    Centralized migration accelerates adaptation and drives parallel evolution, emphasizing the key influence of spatial organization on evolutionary dynamics across systems from pathogen transmission to species range shifts.
    1. Cancer Biology

    PTEN restrains SHH medulloblastma growth through cell autonomous and nonautonomous mechanisms

    Zhimin Lao, Salsabiel El Nagar ... Alexandra L Joyner
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Genetics and Genomics

    Maternal SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven 2-cell totipotency transcriptional program in the mouse embryo

    Tie-Bo Zeng, Zhen Fu ... Piroska E Szabó
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease
    2. Evolutionary Biology

    High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains

    Caroline Kikawa, Andrea N Loes ... Jesse D Bloom
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Neural Connectome of the Ctenophore Statocyst

    Kei Jokura, Sanja Jasek ... Gáspár Jékely
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Toward Robust Neuroanatomical Normative Models: Influence of Sample Size and Covariates Distributions

    Camille Elleaume, Bruno Hebling Vieira ... the Australian Imaging Biomarkers and Lifestyle flagship study of ageing
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics

    RiboTRAP-seq identifies spatially distinct functions for the anterior and posterior intestine in immune and metabolic regulation in C. elegans

    Chung-Chih Liu, Nicolas Seban, Supriya Srinivasan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Specific GPCRs Elicit Unique Extracellular Vesicle MiRNA Array Signatures: An Exploratory Study

    Xiao Shi, Michelle C Palumbo ... Aaron Janowsky
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Executive resources shape the impact of language predictability across the adult lifespan

    Merle Marie Schuckart, Sandra Martin ... Jonas Obleser
    Analyses of self-paced reading times reveal that linguistic prediction deteriorates under limited executive resources, with this resource sensitivity becoming markedly more pronounced with advancing age.
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