Browse our latest research

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    1. Evolutionary Biology

    Super compensatory substitutions restore protein function and flatten fitness landscapes

    Wenhong Jiang, Hengchuang Yin ... Lucas B Carey
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Whole brain mapping of spinal-projecting neurons in larval zebrafish

    Martin Carbo-Tano, Kevin Fidelin ... Claire Wyart
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Computational and Systems Biology

    Protein generation with evolutionary diffusion: sequence is all you need

    Sarah Alamdari, Nitya Thakkar ... Kevin K Yang
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    High basal autophagic activity in the brain revealed by systemic quantitative analysis using GFP-LC3-RFP mice

    Yuki Kanda, Tomoya Eguchi ... Noboru Mizushima
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Polo-like kinase phosphorylation of the orphan kinesin KIN-G negatively regulates centrin arm biogenesis in Trypanosoma brucei

    Yasuhiro Kurasawa, Qing Zhou ... Ziyin Li
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Starvation transforms signal encoding in C. elegans thermoresponsive neurons and suppresses heat avoidance via bidirectional glutamatergic and peptidergic signaling

    Saurabh Thapliyal, Parvathi Sushama Gopinath, Dominique A Glauser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    Olfactory combinatorial coding supports risk-reward decision making in C. elegans

    Md Zubayer Hossain Saad, William G Ryan ... Bruce A Bamber
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Targeted induction of gut-microbial metabolism acutely affects feeding patterns and clock gene expression in the host

    Giorgia Greter, Claudia Moresi ... Markus Arnoldini
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Optimising the tilt increment for in situ cryo-electron tomography

    Maarten Willem Tuijtel, Tomáš Majtner ... Martin Beck
    For in situ cryo-electron tomography, smaller tilt increments yield better-aligned tilt-series and higher-quality tomograms, with a 3° increment resulting in optimal subtomogram averaging resolution.
    1. Cell Biology

    Mitochondrial-derived compartments buffer outer membrane protein load during acute mitochondrial adaptation

    Bo J Price, Sai Sangeetha Balasubramaniam, Adam L Hughes
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
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