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Page 309 of 1,755
    1. Physics of Living Systems

    Hydrodynamics and multiscale order in confluent epithelia

    Josep-Maria Armengol-Collado, Livio Nicola Carenza, Luca Giomi
    Confluent cellular layers display the remarkable ability of supportingmultiscale orientational order, that is the existence of different typeof liquid crystal order at different length scales.
    1. Structural Biology and Molecular Biophysics

    Dissecting Mechanisms of Ligand Binding and Conformational Changes in the Glutamine-Binding Protein

    Zhongying Han, Sabrina Panhans ... Thorben Cordes
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Convincing
    1. Neuroscience

    Dopamine lesions alter the striatal encoding of single-limb gait

    Long Yang, Deepak Singla ... Sotiris C Masmanidis
    Striatal neurons preferentially fire at specific phases of the gait cycle, and the strength of gait encoding is selectively increased in indirect pathway neurons following dopamine lesions.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A novel MARV glycoprotein-specific antibody with potentials of broad-spectrum neutralization to filovirus

    Yuting Zhang, Min Zhang ... Guojiang Chen
    A novel antibody recognizing receptor-binding region of MARV glycoprotein was developed and displays broad-spectrum neutralizing activity to filovirus species when NPC2 was fused to the N-terminus of the mAb.
    1. Cell Biology

    A stable microtubule bundle formed through an orchestrated multistep process controls quiescence exit

    Damien Laporte, Aurelie Massoni-Laporte ... Isabelle Sagot
    In quiescent yeast, a stable bundle of parallel microtubules is assembled from the centrosome by an original multistep mechanism that follows a precise temporality and involves Aurora B and various kinesins.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock

    Daniyal Tariq, Nicole Maurici ... Brian R Crane
    The intrinsic disorder of the circadian clock protein Frequency organizes binding partners, facilitates liquid–liquid phase separation, modulates Frequency phosphorylation, and derives from sequence properties conserved with homologous clock components.
    1. Neuroscience

    Tracking subjects’ strategies in behavioural choice experiments at trial resolution

    Silvia Maggi, Rebecca M Hock ... Mark D Humphries
    A new Bayesian algorithm for tracking subjects’ choice strategies on every trial reveals when subjects learn and what they tried while doing so, providing strong evidence that reward- and loss-driven exploration change independently.
    1. Neuroscience

    TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves

    Matthew Grove, Hyukmin Kim ... Young-Jin Son
    TEAD1 is a major partner transcription factor of YAP/TAZ crucial for developmental myelination and remyelination of peripheral nerves.
    1. Developmental Biology

    Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland

    Qiang Lan, Ewelina Trela ... Marja L Mikkola
    Live imaging, transcriptional profiling and mouse models demonstrated that the mesenchyme controls the growth pace but not the mode of branching of the mammary epithelium and unveiled a unique function for Igf1/Igfr1 in embryonic development mammary gland.
    1. Genetics and Genomics
    2. Neuroscience

    Sibling chimerism among microglia in marmosets

    Ricardo C.H. del Rosario, Fenna M. Krienen ... Steven A. McCarroll
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling