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    1. Immunology and Inflammation

    TLR2 regulates hair follicle cycle and regeneration via BMP signaling

    Luyang Xiong, Irina Zhevlakova ... Tatiana V Byzova
    Cell and animal-based models revealed the new function of TLR2 andcarboxyethylpyrrole as an endogenous TLR2 ligand in the hair follicle cycle in homeostasis and hair follicle regeneration in injury.
    1. Medicine
    2. Neuroscience

    Plasma extracellular vesicle synaptic proteins as biomarkers of clinical progression in patients with Parkinson’s disease

    Chien-Tai Hong, Chen-Chih Chung ... Lung Chan
    The promising potential of plasma extracellular vesicle synaptic proteins as clinical biomarkers of disease progression in Parkinson's disease has been presented.
    1. Developmental Biology
    2. Neuroscience

    Deciphering the genetic interactions between Pou4f3, Gfi1, and Rbm24 in maintaining mouse cochlear hair cell survival

    Guangqin Wang, Yunpeng Gu, Zhiyong Liu
    Rbm24 is controlled by Pou4f3 but not Gfi1 during cochlear hair cell development.
    1. Developmental Biology
    2. Evolutionary Biology

    A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis

    Jaaved Mohammed, Neha Arora ... Joanna Wysocka
    SNP-editing of human embryonic stem cells reveals cell type specific function of a genetic variant associated with changes in human jaw shape.
    1. Neuroscience

    Indistinguishable network dynamics can emerge from unalike plasticity rules

    Poornima Ramesh, Basile Confavreux ... Jakob H. Macke
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease

    Un1Cas12f1 and Cas9 gene drive in HSV1: viruses that ‘infect’ viruses

    Qiaorui Yao, Zhuangjie Lin ... Hongsheng Dai
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Noradrenaline release from the locus coeruleus shapes stress-induced hippocampal gene expression

    Mattia Privitera, Lukas M von Ziegler ... Johannes Bohacek
    Targeted manipulation of the locus coeruleus noradrenaline circuitry combined with extensive transcriptomic analyses in the mouse hippocampus reveal a unique set of noradrenaline-dependent, stress-related genes and point to astrocytic engagement.
    1. Neuroscience

    Causal role of the frontal eye field in attention-induced ocular dominance plasticity

    Fangxing Song, Xue Dong ... Min Bao
    A series of experiments suggest that the fronto-parietal attentional network is involved in controlling eye-based attention, and FEF plays a crucial causal role in generating the attention-induced ocular dominance shift.
    1. Neuroscience

    Structural constraints on the emergence of oscillations in multi-population neural networks

    Jie Zang, Shenquan Liu ... Arvind Kumar
    An odd number of inhibitory links in a network are necessary and sufficient to make a network of neuron populations oscillate.
    1. Structural Biology and Molecular Biophysics

    Structural insights into peptidoglycan hydrolysis by the FtsEX system in Escherichia coli during cell division

    Jianwei Li, Yutong He ... Min Luo
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
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