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The molecular pattern underlying the interactions of opioids with their receptor determines whether membrane depolarization increases or decreases their response or even convert antagonists to agonists.

An atlas of cortical expression for 20,781 genes in the adult human brain, validated against multiscale datasets, from neuroimaging measures of structure and function to molecular cell and layer markers.

We are writing to respond to comment by Sharma et al, 2024 on our article about the antimalarial drug tafenoquine.

We are writing to comment on the article by Watson et al., 2022 about the antimalarial drug tafenoquine.

ChIP-seq analysis reveals BMP signaling targets in a cnidarian and identifies ZSWIM4-6 as a dampener of the pSMAD1/5 gradient and a potential conveyor of the BMP-mediated gene repression.

SIT4 deletion and phosphate starvation increase mitochondrial membrane potential via electron transport chain dependent and independent manners, and the increased membrane potential induced by phosphate depletion is conserved between yeast, flies, and humans.

The iron-sulfur cluster containing Ferredoxin 1 (FDX1), critical in steroidogenesis and TCA cycle, is required for mammalian embryonic development and maintenance of lipid homeostasis at cellular and organismal levels.

New archaeobotanical data from Negev Highland rubbish middens demonstrate that crop diversity in the Southern Levant expanded more during the first millennium CE than in any earlier period, yet with minimal consequences for consumption and production patterns.