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Microcephaly-associated mutations disrupt microtubule-dependent WDR62 translocation from the Golgi complex to the mitotic spindle poles, impair mitotic progression, and alter neurogenic trajectories in patient induced Pluripotent Stem Cell-derived 2D and 3D models of human neurodevelopment.

A large collaborative project combined many different researchers' forecasts of COVID-19 across Europe, making predictions used in policy more reliable.

Cortical cholinergic and noradrenergic signaling contains a strong low-frequency component that is distributed across the mouse cortex and is related to the behavioral state of the animal.

Single-cell multiomics reveals the gene regulatory networks and enhancer logic underlying two distinct wound response cell states in the Drosophila wing imaginal disc and finds similarities with cell states observed in the Ras-scrib tumor model.

Impoverished access to natural human language during early childhood reduces semantic structure encoding in the left dorsal anterior temporal lobe, which provides positive evidence for the role of language in forming specific neural semantic representations in the human brain.

Although courtship vocalizations are unique to each species, the basic architecture of the neural circuitries underlying this behavior is conserved among closely related species of frogs, suggesting behavior can diverge while utilizing the homologous neural network inherited through evolutionary lineage.

The juvenile barn owl displays wide heterogeneity in tuning properties in the auditory midbrain, which is shaped during development to match the pattern of sensory statistics experienced in early life and maintained into adulthood.

STAG proteins function independently of core cohesin at R-loops to facilitate cohesin loading.

Integrated molecular analysis demonstrated that colorectal cancer can be classified into four molecular subtypes (proliferative, immunomodulatory, immunosuppressed, and immune-excluded subtypes), providing valuable insight into the intricate relationship between tumor microenvironment heterogeneity and various clinical phenotypes.

A genetically encoded sensor and a photocaged peptide together enable precise investigation of human glucagon-like peptide-1 receptor activation with high spatiotemporal resolution.