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A novel Mendelian randomisation framework unravels one gene expression component, correlated with proliferation and genome stability-related features, associated with telomere length in lung adenocarcinoma tumours, which provides insights into how telomere length influences the genetic basis of lung cancer aetiology.

Deficiencies of several DNA damage response genes can be predicted by their association with genome-wide mutation patterns.

Comprehensive decade-long analysis of point-of-care resources reveals insights into how clinical research makes its way into practice across different medical specialties and through time to enable us to identify potential translational bottlenecks in the pathway from research to practice.

Single bouton measurements of calcium influx shows that activating GABA_B receptors at nerve terminals can lead to complete inhibition of calcium entry when one is operating at the physiological setpoint of extracellular calcium concentration.

Novel statistical tests to compare networks enable the evaluation of mathematical definitions of left/right symmetry in a larval Drosophila brain connectome.

Flies have two parallel visual pathways with specialized physiological properties to compensate for perturbations in their flight course and to saccade toward objects.

A commonly used immunoglobulin loci-transgenic mouse, the Kymouse, has B cells that go through complete development and have receptor repertoires that show key differences in encoding gene frequencies but structural similarity in their most variable regions.

A proper balance of planar and perpendicular balances is critical to establishing proper epidermal architecture and is mediated by the opposing activities of LGN and its enigmatic paralog AGS3.

Human antibodies that neutralize New World hantaviruses are promising for prevention or treatment of these high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact.

The structure of an NRAMP-related Al³⁺ transporter illustrates the evolution of a branch of a conserved protein family of metal ion transporters in plants to combat Al³⁺ toxicity in acidic soil.