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Page 469 of 1,762
    1. Computational and Systems Biology

    Longitudinal fundus imaging and its genome-wide association analysis provide evidence for a human retinal aging clock

    Sara Ahadi, Kenneth A Wilson ... Ali Bashir
    Deep learning on fundus images provides a non-invasive, short time-scale biological aging clock that successfully identifies aging genes validated in a fly model.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Glia-neuron coupling via a bipartite sialylation pathway promotes neural transmission and stress tolerance in Drosophila

    Hilary Scott, Boris Novikov ... Vladislav Panin
    The sialylation pathway is uniquely partitioned in Drosophila between glia and neurons and mediates a novel mechanism of glia-neuron coupling that regulates neural functions, promotes tolerance to heat and oxidative stress, and maintains the normal level of voltage-gated sodium channels.
    1. Neuroscience

    Spatiotemporal organisation of human sensorimotor beta burst activity

    Catharina Zich, Andrew J Quinn ... Sven Bestmann
    Burst activity can be described in all three signal domains and sensorimotor beta burst activity propagates along two axes either parallel or perpendicular to the central sulcus.
    1. Cell Biology

    Single-cell RNA-seq of heart reveals intercellular communication drivers of myocardial fibrosis in diabetic cardiomyopathy

    Wei Li, Xinqi Lou ... Shigang Qiao
    Cardiac intercellular communication plays a critical role in diabetic myocardial fibrosis and specific targeting of Hrchi fibroblasts may be a potential therapeutic target for diabetic cardiomyopathy.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    An optimal regulation of fluxes dictates microbial growth in and out of steady state

    Griffin Chure, Jonas Cremer
    Microbial cells optimally structure their proteomes in order to mutually maximize metabolism and translation, as established by an extensive comparison between data and a low-dimensional model of cellular physiology.
    1. Epidemiology and Global Health
    2. Immunology and Inflammation

    Evaluation of antibody kinetics and durability in healthy individuals vaccinated with inactivated COVID-19 vaccine (CoronaVac): A cross-sectional and cohort study in Zhejiang, China

    Hangjie Zhang, Qianhui Hua ... Huakun Lv
    Serum antibodies induced by CoronaVac tended to decrease over time, even though vaccinated with the homologous booster dose, and Delta and Omicron variants may be able to more efficiently evade the antibodies with time.
    1. Computational and Systems Biology
    2. Ecology

    Emergent regulation of ant foraging frequency through a computationally inexpensive forager movement rule

    Lior Baltiansky, Guy Frankel, Ofer Feinerman
    Rather than complex decisions, it is the motion of individuals that allows for collective foraging regulation in ant colonies.
    1. Neuroscience

    Striatal ensemble activity in an innate naturalistic behavior

    Samuel Minkowicz, Mychaela Alexandria Mathews ... Yevgenia Kozorovitskiy
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Integration host factor regulates colonization factors in the bee gut symbiont Frischella perrara

    Konstantin Schmidt, Gonçalo Santos-Matos ... Philipp Engel
    Genes for adhesion, interbacterial competition, and secondary metabolite production are important colonization factors of the honey bee gut symbiont Frischella perrara and are regulated by the conserved histone-like DNA-binding protein integration host factor.
    1. Neuroscience

    Memory for incidentally learned categories evolves in the post-learning interval

    Yafit Gabay, Avi Karni, Lori L Holt
    Incidental experiences can lead to lasting category knowledge, demonstrating that humans forage for information to acquire and consolidate new knowledge even when learning is not strictly necessary for success on an ongoing task.