Browse our latest research

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    1. Ecology
    2. Evolutionary Biology

    Windborne migration amplifies insect-mediated pollination services

    Huiru Jia et al.
    Delineating Episyrphus balteatus transregional movements and pollination networks advance a deep understanding of its migration ecology and facilitate the design of targeted strategies to conserve and enhance its ecosystem services.
    1. Biochemistry and Chemical Biology

    Inhibitory proteins block substrate access by occupying the active site cleft of Bacillus subtilis intramembrane protease SpoIVFB

    Sandra Olenic, Lim Heo ... Lee Kroos
    A novel mechanism of intramembrane protease regulation involves a protein blocking the active site of the enzyme.
    1. Neuroscience

    Opioid analgesia alters corticospinal coupling along the descending pain system in healthy participants

    Alexandra Tinnermann, Christian Sprenger, Christian Büchel
    Corticospinal functional MRI reveals that the opioid remifentanil and the level of perceived analgesia modulate coupling strength between the prefrontal cortex, brainstem, and spinal cord.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Free spermidine evokes superoxide radicals that manifest toxicity

    Vineet Kumar, Rajesh Kumar Mishra ... Dipak Dutta
    Spermidine-mediated superoxide generation affects iron homeostasis in Escherichia coli.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development

    Eric Van Otterloo, Isaac Milanda ... Trevor Williams
    In addition to a neural crest cell specific role, AP-2α and AP-2ß cooperatively promote craniofacial development through regulating chromatin and gene expression dynamics in the facial surface ectoderm.
    1. Developmental Biology

    Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells

    Di Peng, Koji Ando ... Katarzyna Koltowska
    Spatio-temporal analysis using live imaging in zebrafish reveals mural cells as a source of pro-lymphangiogenic factors including chemokine and growth factor signalling, necessary for robust lymphatic endothelial cell migration and survival.
    1. Immunology and Inflammation
    2. Medicine

    Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection

    Noah J Silverstein, Yetao Wang ... Jeremy Luban
    Homeostatic innate lymphoid cell abundance, adjusted for age and sex, correlates inversely with COVID-19 severity in adults and children.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    The ACF chromatin-remodeling complex is essential for Polycomb repression

    Elizabeth T Wiles, Colleen C Mumford ... Eric U Selker
    The ACF chromatin-remodeling complex positions the +1 nucleosome in facultative heterochromatin to mediate transcriptional repression at Polycomb target genes.
    1. Neuroscience

    Perception is associated with the brain’s metabolic response to sensory stimulation

    Mauro DiNuzzo, Silvia Mangia ... Federico Giove
    Perceived and unperceived visual stimuli that are contrast matched to produce similar BOLD responses in V1 elicit clearly distinct changes in the neurochemical profile, implying a perception-related dissociation between neurometabolic and neurovascular response.
    1. Medicine

    Meta-research: justifying career disruption in funding applications, a survey of Australian researchers

    Adrian Barnett, Katie Page ... Susanna Cramb
    A survey of health and medical researchers revealed important diffrences in how career disruption is treated in funding decisions, with differences in what applicants with disruption are willing to divulge and the adjustments made by reviewers.