Paula Kaanders, Pradyumna Sepulveda ... Benedetto De Martino
In a perceptual choice task, human participants have a preference for sampling more information from a previously chosen alternative, indicating the presence of 'confirmation bias' in perceptual decision-making.
A parametrization-invariant synaptic plasticity rule based on natural-gradient descent leads to multiple predictions for the biological plasticity process, some of which relate to well-studied phenomena such as heterosynaptic plasticity.
Leah J Greenspan, Margaret de Cuevas ... Erika L Matunis
In the adult Drosophila testis, normally quiescent niche cells can be forced to re-enter the cell cycle and give rise to new stem cells in response to epidermal growth factor receptor signaling.
A cellular and biophysical study on embryonic stem cell aggregates reveals that the endoderm can form by a three-step mechanism involving a Wnt/beta-catenin-mediated epiblast fragmentation, tissue flow and cell segregation.
Computational simulations of actin network growth at the cell leading edge, combined with careful high-speed video microscopy measurements of leading edge shape fluctuations, suggest that Arp2/3 branching of the actin network occurs at an optimal angle to minimize fluctuations.
Marcus M Weera, Abigail E Agoglia ... Nicholas W Gilpin
A novel transgenic rat for studying the role of specific corticotropin-releasing factor type-1 receptor-expressing cell populations in physiology and behavior.
Zheng Zhou, Valentyna Krashevska ... Anton Potapov
Tropical land use makes most soil animal groups shift to 'fast' energy channel and restructures soil food web at community level, but this change is buffered by earthworms at ecosystem (energetic) level.
The proteasomal deubiquitinase UCHL5/UCH37 uses a face distinct from the canonical ubiquitin binding site to engage K48-linked ubiquitin chains and catalyze chain debranching.
