Browse our latest research

Page 639 of 1,737
    1. Epidemiology and Global Health
    2. Medicine

    Ontogeny of circulating lipid metabolism in pregnancy and early childhood – a longitudinal population study

    Satvika Burugupalli, Adam Alexander T Smith ... Barwon Infant Study Investigator team
    Plasma lipidomic profiling in pregnancy, infancy and early childhood provides a framework to define the relationship between lipid metabolism and health outcomes in early childhood.
    1. Neuroscience

    Intrinsic mechanical sensitivity of mammalian auditory neurons as a contributor to sound-driven neural activity

    Maria C Perez-Flores, Eric Verschooten ... Ebenezer N Yamoah
    In vitro and in vivo physiological analyses reveal that mammalian auditory neuron intrinsic mechanical sensitivity contributes to sound-evoked activity and explains other previously unexplained auditory neuron features.
    1. Cell Biology
    2. Physics of Living Systems

    Cortical waves mediate the cellular response to electric fields

    Qixin Yang, Yuchuan Miao ... Wolfgang Losert
    Electrical and biomechanical stimuli directly bias cortical signal transduction and cytoskeletal waves, and the direct bias induced by an electric field develops slowly compared to the rapid surface-receptor-mediated response to chemotactic gradients.
    1. Medicine

    Post-acute sequelae of COVID-19: A metabolic perspective

    Philipp E Scherer, John P Kirwan, Clifford J Rosen
    The potential metabolic mechanisms that underly the growing prevalence of long COVID are explored and potential treatments discussed.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    MicroRNA 3′-compensatory pairing occurs through two binding modes, with affinity shaped by nucleotide identity and position

    Sean E McGeary, Namita Bisaria ... David P Bartel
    Affinity measurements of microRNA sites representing >1000 different pairing architectures reveal that two binding modes can mediate pairing to the microRNA 3′ region, and that microRNA G and oligo(G/C) residues are most impactful.
    1. Epidemiology and Global Health
    2. Medicine

    Risk of heart disease following treatment for breast cancer – results from a population-based cohort study

    Haomin Yang, Nirmala Bhoo-Pathy ... Kamila Czene
    Long-term increased risks of arrhythmia and heart failure were found in breast cancer patients, while systemic adjuvant therapies including trastuzumab and anthracyclines were associated with the increased risk of heart failure.
    1. Neuroscience

    Telencephalic outputs from the medial entorhinal cortex are copied directly to the hippocampus

    Sau Yee Tsoi, Merve Öncül ... Gülşen Sürmeli
    A novel pathway from the deep entorhinal cortex to the hippocampus suggests that the hippocampal–neocortical loop is supported by a feedback projection from the entorhinal deep layers that copies entorhinal output to the hippocampus.
    1. Evolutionary Biology

    Phylogenomic analyses of echinoid diversification prompt a re-evaluation of their fossil record

    Nicolás Mongiardino Koch, Jeffrey R Thompson ... Greg W Rouse
    Phylogenomics of sea urchins clarifies their origins and diversification history, reveals surprising discrepancies with their rich fossil record, and serves as basis to explore the sensitivity of time calibration analysis.
    1. Developmental Biology
    2. Neuroscience

    Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity

    Catarina Catela, Yihan Chen ... Paschalis Kratsios
    Molecular, genetic, and behavioral assays in mice establish a new role for Hox proteins in the final steps of spinal motor neuron development.
    1. Developmental Biology
    2. Neuroscience

    Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

    Ryoji Amamoto, Grace K Wallick, Constance L Cepko
    Retinoic acid signaling from Muller glia is necessary for cone photoreceptor survival in the peripheral retina and is sufficient to promote cone survival in the central retina during retinal degeneration.