Browse our latest research

In vivo whole-cell recordings in the piriform cortex show that two classes of layer 1 interneurons respond differently to odors, suggesting that these neurons provide kinetically distinctive types of odor-evoked feedforward inhibition.

Cell encapsulation-based transcriptional profiling using myogenic progenitors reveals that long-range factors in the aged systemic environment induce a wide range of signaling pathways in a niche-independent manner.

Pseudomonas aeruginosa defends against interbacterial antagonism through the coordinated expression of previously uncharacterized pathways that grant threat-specific protection.

A transcriptional coactivator turns into a repressor at specific genes in colorectal cancer cells.

Tom70 connects the mitochondrial import to the nuclear transcriptional activity of mitochondrial proteins and controls mitochondrial biogenesis defects during aging.

Genome-wide analyses reveal how tumor-associated mutations of the Fbw7 ubiquitin ligase impact oncogenic transcription factors and gene expression.

Visualization of the real-time conformational transitions of the human voltage-gated proton channel hHv1 provided novel insights into how voltage and pH gradients modify the dynamic behaviors of channel structures to control proton flow across membrane.

A phase transition of TIR-1/SARM1 induced by either pathogen or non-pathogen stress potentiates its intrinsic NADase activity, which activates the p38 PMK-1 signaling cascade to induce protective immune defenses in Caenorhabditis elegans intestinal epithelial cells.

Inflammatory responses mediated by gasdermins are important for adequate fracture healing.

Neuroimaging proves to be a powerful tool for capturing spatial and temporal dynamics across the whole nonhuman primate brain, bridging the gap between human and animal models.