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Humans can predict and optimally plan goal-directed dynamic walking tasks that have transient events such as negotiating a sidewalk curb.

High mortality following traumatic brain injury in mice carrying a human mutation for familial hemiplegic migraine type 1 (FHM1) is caused by a decreased threshold for cortical spreading depolarizations (CSDs) and subsequent brain edema formation.

Integrated live cell imaging and image analyses in the framework of transition path theories identify epithelial-to-mesenchymal transition proceeds through parallel paths.

Many V1 double-opponent cells integrate light information across their receptive fields as linearly as simple cells do.

Electrophysiology, optogenetics, and imaging in a mouse model of Dravet syndrome reveals dentate gyrus circuit dysfunction driven by hyperexcitability of the perforant path input from entorhinal cortex that can be modulated by recruitment of parvalbumin-expressing inhibitory interneurons.

Axon degeneration due to loss of mitochondria is suppressed by CaMKII activity and MAP kinase signaling.

Genetic and mechanistic analyses reveal how ovulatory rupture triggers the activation and expansion of ovarian surface epithelial stem/progenitor cells, through selective activation of Yap, and enhanced expression of Procr by Yap.

Dropouts in single cell RNA sequencing data are associated with cell states and can affect gene signature scoring if methods do not account for them.

The X-ray crystal structure of the unusual carbon–carbon bond-forming biosynthetic enzyme CylK reveals a unique biochemical strategy for selective alkyl halide activation and substitution.

Apelin signaling-dependent endocardial protrusions promote cardiac trabeculation through Nrg/ErbB/Erk signaling in zebrafish.