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Page 73 of 1,794
    1. Evolutionary Biology

    Cryptovaranoides is not a squamate

    Michael W Caldwell, Chase D Brownstein ... Tiago R Simões
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Cancer Biology

    The 1000+ mouse project: large-scale spatiotemporal parametrization and modeling of preclinical cancer immunotherapies

    Adam L Kenet, Sooraj Achar ... Grégoire Altan-Bonnet
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Computational and Systems Biology

    Targeted Computational Design of an Interleukin-7 Superkine with Enhanced Folding Efficiency and Immunotherapeutic Efficacy

    See-Khai Lim, Wen-Ching Lin ... Kurt Yun Mou
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Domain coupling in allosteric regulation of SthK measured using time-resolved transition metal ion FRET

    Pierce Eggan, Sharona E Gordon, William N Zagotta
    Time-resolved fluorescence resonance energy transfer reveals conformational energetics of a bacterial cyclic nucleotide-gated ion channel.
    1. Neuroscience

    A tight relationship between BOLD fMRI activation/deactivation and increase/decrease in single neuron responses in human association cortex

    Marie-Alphée Laurent, Corentin Jacques ... Bruno Rossion
    There is a striking correspondence between face-selective neural increases vs decreases of fMRI BOLD signal and spikes in neighboring human fusiform gyrus regions.
    Version of Record
    Short Report
    • Valuable
    • Solid
    1. Evolutionary Biology
    2. Ecology

    Weak evidence for heritable changes in response to selection by aphids in Arabidopsis accessions

    Marc W Schmid, Klara Kropivšek ... Ueli Grossniklaus
    Strong selection by aphids only weakly affects epigenetic and phenotypic variation within three Arabidopsis thaliana accessions, demonstrating limited potential for adaptation by epigenetic differentiation within genotypes in this model species.
    1. Developmental Biology

    An increase in reactive oxygen species underlies neonatal cerebellum repair

    Anna Pakula, Salsabiel El Nagar ... Alexandra L Joyner
    During cerebellum regeneration following injury, reactive oxygen species are implicated as enhancing the adaptive reprogramming response that contributes to replenishment of granule cell progenitors that are killed.
    1. Evolutionary Biology

    Iridescent structural coloration in a crested Cretaceous enantiornithine bird from the Jehol Biota

    Zhiheng Li, Jinsheng Hu ... Julia A Clarke
    The combination of histological and microscopic techniques, along with the initial application of finite-difference time-domain (FDTD) modeling to a fossil feather, has resulted in the first recovery of specific iridescent color patterns.
    1. Medicine

    Early menarche and childbirth accelerate aging-related outcomes and age-related diseases: Evidence for antagonistic pleiotropy in humans

    Yifan Xiang, Vineeta Tanwar ... Pankaj Kapahi
    Mendelian randomization offers novel insights into the genetic factors that influence the aging process through early-life reproductive events, providing robust evidence for the antagonistic pleiotropy theory in humans.