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    1. Developmental Biology

    Mural cells protect the adult brain from hemorrhage but do not control the blood–brain barrier in developing zebrafish

    Oguzhan F Baltaci, Andrea Usseglio Gaudi ... Benjamin M Hogan
    Pericytes regulate cerebrovascular development, while vascular smooth muscle cells prevent hemorrhage and blood–brain barrier breakdown at vascular hotspots in juvenile and adult zebrafish.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A miniaturized MR1 metabolite display system with native-like protein features

    Photis Rotsides, Omkar Shinde ... Nikolaos G Sgourakis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Evolutionary Biology

    Bacterial ancestry of the mitochondrial ATP exporter

    Jotin Gogoi, Rajan Sankaranarayanan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Examining Alzheimer’s Disease modifiable risk factors: Impact of physical activity and diet on neuroanatomy and behaviour in mouse models

    Cindy L García, Chloe Anastassiadis ... M Mallar Chakravarty
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Decentralized Clocks and Direct Photoreception: The Zebrafish as an Integrative Model for Circadian Biology

    Wang Liao, Chun-jiao Wei ... Da-long Ren
    Not revised
    Reviewed Preprint v1
    1. Genetics and Genomics
    2. Plant Biology

    Uncovering genetic mechanisms underlying trait variation in switchgrass using explainable artificial intelligence

    Paulo Izquierdo, Xiaoyu Weng ... Shin-Han Shiu
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    When word order matters: human brains represent sentence meaning differently from large language models

    James Fodor, Carsten Murawski, Shinsuke Suzuki
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Computational and Systems Biology

    Generative modeling for RNA splicing prediction and design

    Di Wu, Natalie Maus ... Yoseph Barash
    TrASPr+BOS enables accurate prediction and design of tissue-specific RNA splicing, even for tissues not trained on, uncovering unseen regulatory elements and guiding sequence edits that reshape splicing outcomes.
    1. Cell Biology

    Ubiquitin ligase ITCH regulates life cycle of SARS-CoV-2 virus

    Qiwang Xiang, Camille Wouters ... Jiou Wang
    ITCH is an important regulator of SARS-CoV-2 life cycle, coordinating ubiquitination, assembly, autophagosome-mediated secretion, and spike stability, highlighting ITCH as a promising therapeutic target for antiviral intervention.
    1. Neuroscience

    Capturing learning on the fly: an eye-tracking method to quantify prediction errors and updating the prior

    Flóra Hann, Cintia Anna Nagy ... Orsolya Pesthy
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
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