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Page 73 of 1,884
    1. Immunology and Inflammation

    Cas9+ conditionally immortalized neutrophil progenitors as a tool for genome-wide CRISPR screening for neutrophil differentiation and function

    Robyn M Jong, Krystal L Ching ... Sarah A Stanley
    Cas9+ER-Hoxb8 neutrophils are a new tool for investigating neutrophil biology in vitro and in vivo.
    1. Developmental Biology

    HSD17B7 is required for the function of sensory hair cells by regulating cholesterol synthesis

    Yuqian Shen, Ziyang Wang ... Dong Liu
    HSD17B7-dependent cholesterol biosynthesis is essential for hair cell function, implicating HSD17B7 disruption in the pathogenesis of hearing loss.
    1. Cell Biology
    2. Neuroscience

    CO2-dependent opening of connexin 43 hemichannels

    Valentin Mihai Dospinescu, Alexander Mascarenhas ... Nicholas Dale
    Connexin43 is the most ubiquitously expressed connexin in the human body, and the CO2-dependent opening of Connexin43 hemichannels implies that CO2 may influence many physiological processes.
    1. Neuroscience

    Divergent spatiotemporal integration of whole-field visual motion in medaka and zebrafish larvae

    Yasuko Isoe, Yasmine Fatima Mabene ... Florian Engert
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Intron Retention Controls Localization of lncRNAs PURPL and MALAT1 to Promote Cell Proliferation and Migration

    Ioannis Grammatikakis, Chosita Norkaew ... Ashish Lal
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    • Compelling
    1. Cell Biology
    2. Neuroscience

    A validated antibody toolbox for ALS research

    Riham Ayoubi, Emma J MacDougall ... Carl Laflamme
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology
    2. Neuroscience

    ARHGEF6-dependent cytoskeletal regulation underlies a conserved program of forebrain interneuron development

    Carla Liaci, Beatrice Savarese ... Giorgio R Merlo
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Modality-Specific and Amodal Language Processing by Single Neurons

    Yair Lakretz, Naama Friedmann ... Itzhak Fried
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Dissecting mechanisms of ligand binding and conformational changes in the glutamine-binding protein

    Zhongying Han, Sabrina Panhans ... Thorben Cordes
    A range of biophysical techniques is used in combination with computational analysis to understand whether glutamine-binding protein binds its ligand via the induced-fit or conformational selection mechanism.
    1. Chromosomes and Gene Expression

    Interplay between cohesin and TORC1 links chromosome segregation and gene expression to environmental changes

    Dorian Besson, Sabine Vaur ... Jean-Paul Javerzat
    A conserved kinase network links nutrient sensing to chromosome segregation and gene regulation by modulating cohesin dynamics through phosphorylation.
    Version of Record
    Research Article
    • Important
    • Compelling
    • Convincing
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