Browse our latest research

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    1. Neuroscience

    Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling

    Stephan Tetenborg, Eyad Shihabeddin ... John O’Brien
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology

    Generative modeling for RNA splicing prediction and design

    Di Wu, Natalie Maus ... Yoseph Barash
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Locus coeruleus modulation of single-cell representation and population dynamics in the mouse prefrontal cortex during attentional switching

    Marco Nigro, Lucas Silva Tortorelli ... Hongdian Yang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Ecology

    The urban tree of life: quantifying relationships between body size and urban tolerance for more than 30,000 plant and animal species

    Corey T Callaghan, Diana E Bowler ... Thomas Merckx
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    DANCE provides an open-source and low-cost approach to quantify aggression and courtship in Drosophila

    R Sai Prathap Yadav, Paulami Dey ... Pavan Agrawal
    A low-cost, portable platform combining machine learning–based classifiers enables accurate quantification of Drosophila aggression and courtship, expanding access to behavioral neuroscience in resource-limited settings.
    1. Cancer Biology

    Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer

    Jessica Armand, Sungsoo Kim ... Hee Won Yang
    Maintaining CDK4/6 inhibition constrains drug‑resistant breast tumors by delaying cell‑cycle entry, and adding CDK2 inhibition further deepens control to guide post‑progression therapy.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Glycosylated IgG antibodies contribute to the recovery of haemorrhagic fever with renal syndrome patients

    Chuansong Quan, Lu Wang ... Haifeng Hou
    Increased fucosylated IgG and reduced bisecting GlcNAc during HTNV convalescence may promote rapid recovery from hemorrhagic fever with renal syndrome.
    Version of Record
    Short Report
    • Valuable
    • Solid
    1. Medicine
    2. Neuroscience

    Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia

    Naidi Sun, Yu-Yo Sun ... Song Hu
    Post‑HI oxidative‑phosphorylation uncoupling drives secondary energy failure in neonatal brains, and preventing the post‑HI CMRO2 surge is a key mechanism underlying hypothermia’s neuroprotection.
    1. Microbiology and Infectious Disease

    A system for functional studies of the major virulence factor of malaria parasites

    Jakob Cronshagen, Johannes Allweier ... Tobias Spielmann
    The generation of malaria parasites expressing only one of the multiple variants of their most important virulence factor enables the study of different aspects of this virulence factor.