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    1. Evolutionary Biology

    Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant (Ooceraea biroi)

    Kip D Lacy, Jina Lee ... Daniel JC Kronauer
    A complementary sex determination locus is conserved in ants and dates back to approximately 112 million years ago.
    1. Immunology and Inflammation

    Layers of immunity: Deconstructing the Drosophila effector response

    Faustine Ryckebusch, Yao Tian ... Bruno Lemaitre
    New tools make it possible to investigate the timing and importance of different immune effectors in defense against infection.
    1. Neuroscience

    Recovery of the full in vivo firing range in post-lesion surviving DA SN neurons associated with Kv4.3-mediated pacemaker plasticity

    Lora Kovacheva, Josef Shin ... Jochen Roeper
    Dopamine midbrain neurons surviving a lesion slowly recover their in vivo firing patterns by homeostatic pacemaker acceleration mediated by Kv4.3 channel downregulation.
    1. Microbiology and Infectious Disease

    Quinolines interfere with heme-mediated activation of artemisinins

    Melissa R Rosenthal, Daniel E Goldberg
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology

    Integrated Respirometry and Metabolomics Unveil Circadian Metabolic Dynamics in Drosophila

    Farheen Akhtar, Dania Malik ... Aalim M Weljie
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Medicine

    Cell-autonomous and non-cell-autonomous effects of Arginase 2 on cardiac aging

    Duilio M Potenza, Xin Cheng ... Xiu-Fen Ming
    Arginase 2 in macrophages promotes cardiac aging phenotype via paracrine release of IL-1β.
    1. Neuroscience

    Characterization of postsynaptic glutamate transporter functionality in the zebrafish retinal first synapse across different wavelengths

    Marco Garbelli, Stephanie Niklaus, Stephan CF Neuhauss
    Loss of the glutamate transporters EAAT5b and EAAT7 disrupts wavelength-specific visual processing and UV-dependent prey detection in zebrafish, revealing their key roles in modulating light integration and behaviorally relevant vision.
    1. Neuroscience

    Misclassification in memory modification in AppNL-G-F knock-in mouse model of Alzheimer’s disease

    Mei-Lun Huang, Yusuke Suzuki ... Itaru Imayoshi
    Computational modeling of the memory modification process reveals biased internal states in an Alzheimer’s disease mouse model, providing a new approach for early cognitive assessment and diagnosis.
    1. Computational and Systems Biology
    2. Neuroscience

    Correlation detection as a stimulus computable account for audiovisual perception, causal inference, and saliency maps in mammals

    Cesare V Parise
    Optimal cue integration, Bayesian Causal Inference, spatial orienting, speech illusions and other key phenomena in audiovisual perception naturally emerge from the collective behavior of a population of Multisensory Correlation Detector.
    1. Cell Biology

    Vesiculation pathways in clathrin-mediated endocytosis

    Xinran Wang, Julien Berro, Rui Ma
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid