Sarah E Sandkuhler, Kayla S Youngs ... Samuel J Mackenzie
Evidence from multiple model systems supports a shift away from heme transport and toward metabolic dysfunction and oxidative stress as key drivers of TANGO2 deficiency.
A replication stress–ELF3 axis enables luminal progenitor transformation in BRCA1-deficient breast cancer by reducing genomic instability and promoting progenitor identity.
Michaela T Reichmann, Liku B Tezera ... Paul T Elkington
The deep evolutionary relationship between humans and Mycobacterium tuberculosis suggests latent infection may confer benefit, with important consequences for investigating and interpreting host–pathogen interactions.
Kyle Spinler, Michael Hamilton ... Tannishtha Reya
A naturally occurring Musashi2 genetic translocation reported to occur in blast crisis chronic myelogenous leukemia patients can act as an oncogene and drive myeloid leukemia.
Alexander S Teplenin, Nina N Kudryashova ... Tim De Coster
Collective frequency-selective resonance in depolarised cardiac tissue enables reversible switching between quiescent and ectopic oscillations through hidden bi-stability, which is shaped by light intensity, illuminated area, and pacing frequency.
