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Endotoxemia recruits fast-acting anti-inflammatory innate myeloid progenitors from bone marrow into regional lymphatics through release of pre-formed Ccl19 secondary to NF-κB-independent, Traf6/IκB kinase-dependent signaling.

Prokaryotes use polycistronic messages for coordinated translation, whereas eukaryotic cells may achieve tunable protein synthesis by packaging monocistronic mRNAs into functional multiplexes via co-transcriptional interallelic coupling and non-canonical histone-H4 functions.

An unbiased proteomics approach in human cells identifies ZC3H4 and shows that it is important for controlling the transcription of unstable RNA synthesized upstream of promoters and over enhancers.

A new three-step monosynaptic premotor tracing strategy in adult mice, together with registration to the Allen mouse common coordinate framework, uncovered precise spatial relationships of distinct orofacial premotor circuits in the brainstem.

A standard for complex mouse behavior that can be successfully reproduced across laboratories, along with open-access data and tools to implement provide a resource for reproducibility through collaborative open-science approaches.

Mechanical competition is controlled by biophysical parameters that regulate cellular homeostatic density, while biochemical competition is regulated by parameters that influence the organisation of cells in a tissue.

Distinct dorsal periaqueductal gray ensembles encode threat approach and avoidance behavioral states.

Purine biosynthesis is reduced in humans due to a single amino acid substitution in adenylosuccinate lyase that occurred subsequent to the divergence of modern humans from Neandertals.

By linking export and licensing of a piRNA precursor transcript, channel nuclear pore complex subunits Nup54 and Nup58 are specifically required to silence transposons in the Drosophila ovary.

Radial patterns of cell morphology in the Drosophila larval wing emerge through mechanosensitive dynamics of cell polarity.