Specific localization of KRAS downstream target ARL4C with its novel interacting proteins was the active site of invasion of pancreatic cancer cell and induced metastasis.
Michael C Kiritsy, Katelyn McCann ... Andrew J Olive
Complex I of the mitochondrial respiratory chain is necessary for interferon gamma-mediated responses in antigen-presenting cells and is required for CD4+ T cell activation.
María J Conde-Dusman, Partha N Dey ... Isabel Perez-Otaño
Non-conventional NMDA receptors containing GluN3A subunits place constraints on the capacity of the brain to encode lasting memories through regulation of synaptic GIT1/mTOR signaling complexes.
The protein components of an essential and conserved meiotic interface, the synaptonemal complex, have highly conserved coil-coiled domains and protein length, despite highly diverged sequence.
Benedetta De Ponte Conti, Annarita Miluzio ... Sara Ricciardi
In the tumor microenvironment, only specific subsets of cytotoxic and immunosuppressive tumor-infiltrating lymphocytes are endowed with active translation.