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Plant meristem size and shape is controlled by two intertwined regional feedback signals that are mediated by secreted peptides.

Goblet cells use distinct receptors and signaling pathways to independently perform mucus secretion and endocytosis of fluid-phase cargo with atypical trafficking to deliver lumenal substances to the immune system.

Genomics-based evidence support population- and sex-specific selection of an epistatic interaction between genetic variants in ADCY9 and CETP, genes of pharmacogenetic importance in cardiovascular diseases.

Reactive oxygen species can activate the ATR/Chk1 pathway in the absence of detectable DNA damage and without a requirement for DNA damage response proteins.

Prairie and meadow voles show striking sex and species differences in social motivation to access conspecifics of different types (familiar versus unfamiliar and same-sex versus opposite-sex).

A switch-like cell fate divergence revealed by continuous single-cell tracking during entry into quiescence.

The mouse rod photoreceptor ribbon creates a large number of releasable vesicles with uniform release kinetics.

Electrophysiology experiments with genetic and pharmacological manipulations identify a role for astrocyte GluN2C NMDA receptors in maintaining the broad range of presynaptic strengths, which is suggested by numerical simulations to enhance the expression of synaptic plasticity.

Drosophila females store more fat than males because the presence of a functional Transformer protein in females limits adipokinetic hormone production and pathway activity.

A novel bacterial single-cell growth mode is identified in C. glutamicum, which sheds light on its elongation dynamics and cell size regulation.