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Page 939 of 1,750
    1. Neuroscience

    Experience, circuit dynamics, and forebrain recruitment in larval zebrafish prey capture

    Claire S Oldfield, Irene Grossrubatscher ... Ehud Y Isacoff
    Experience strengthens hunting in larval zebrafish by recruiting the forebrain to increase the prey-evoked activity in visual areas and trigger motor activity and prey capture.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor

    Gabrielle E Giese, Melissa D Walker ... Albertha JM Walhout
    Metabolic activity of the methionine/S-adenosylmethionine cycle is sensed and transcriptionally regulated by a nuclear hormone receptor in Caenorhabditis elegans in order to maintain metabolic homeostasis in a tightly controlled regime.
    1. Neuroscience

    External location of touch is constructed post-hoc based on limb choice

    Femke Maij, Christian Seegelke ... Tobias Heed
    Humans retrospectively localize touch after deciding on which limb it occurred, challenging the mainstream idea that tactile location in space is the basis for assigning touch to a body part.
    1. Neuroscience

    A dual role for Cav1.4 Ca2+ channels in the molecular and structural organization of the rod photoreceptor synapse

    J Wesley Maddox, Kate L Randall ... Amy Lee
    Ca2+ influx through Cav1.4 channels is required for the structural, but not the molecular organization of the rod photoreceptor synapse.
    1. Neuroscience

    Purkinje cell neurotransmission patterns cerebellar basket cells into zonal modules defined by distinct pinceau sizes

    Joy Zhou, Amanda M Brown ... Roy V Sillitoe
    Targeted genetic silencing and reporter labeling reveal that Purkinje cell activity organizes cerebellar basket cells into zonal modules based on the sizes of their projections.
    1. Neuroscience

    nNOS-expressing interneurons control basal and behaviorally evoked arterial dilation in somatosensory cortex of mice

    Christina T Echagarruga, Kyle W Gheres ... Patrick J Drew
    The diameter of cortical arteries is not controlled by the overall neural activity, but rather by a subset of specialized neurons.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast

    Sara N Mouton, David J Thaller ... Liesbeth M Veenhoff
    In mitotically aging yeast cells, the cytosol acidifies, the distances between the organellar membranes decrease dramatically, but crowding on the scale of the average size protein is relatively stable.
    1. Developmental Biology

    Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks

    Kelsey H Elliott, Xiaoting Chen ... Samantha A Brugmann
    Context-dependent optimization of Gli-binding site occupancy, in the presence of Hand2, is critical for modulating tissue-specific transcriptional output within tissues that lack an obvious Hedgehog morphogen gradient.
    1. Neuroscience

    The role of cochlear place coding in the perception of frequency modulation

    Kelly L Whiteford, Heather A Kreft, Andrew J Oxenham
    Human perceptual sensitivity to frequency modulation across the hearing range can be explained by a unitary neural code based on neural responses to amplitude modulation and fidelity of cochlear tuning.
    1. Neuroscience

    The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo

    Cedric Bressan, Alessandra Pecora ... Armen Saghatelyan
    Imaging of energy status and autophagy during neuronal migration revealed that ATP/ADP levels dynamically change during the migratory and stationary phases and that ATP reduction induces autophagy to maintain migration.