Claire S Oldfield, Irene Grossrubatscher ... Ehud Y Isacoff
Experience strengthens hunting in larval zebrafish by recruiting the forebrain to increase the prey-evoked activity in visual areas and trigger motor activity and prey capture.
Gabrielle E Giese, Melissa D Walker ... Albertha JM Walhout
Metabolic activity of the methionine/S-adenosylmethionine cycle is sensed and transcriptionally regulated by a nuclear hormone receptor in Caenorhabditis elegans in order to maintain metabolic homeostasis in a tightly controlled regime.
Humans retrospectively localize touch after deciding on which limb it occurred, challenging the mainstream idea that tactile location in space is the basis for assigning touch to a body part.
Targeted genetic silencing and reporter labeling reveal that Purkinje cell activity organizes cerebellar basket cells into zonal modules based on the sizes of their projections.
Sara N Mouton, David J Thaller ... Liesbeth M Veenhoff
In mitotically aging yeast cells, the cytosol acidifies, the distances between the organellar membranes decrease dramatically, but crowding on the scale of the average size protein is relatively stable.
Kelsey H Elliott, Xiaoting Chen ... Samantha A Brugmann
Context-dependent optimization of Gli-binding site occupancy, in the presence of Hand2, is critical for modulating tissue-specific transcriptional output within tissues that lack an obvious Hedgehog morphogen gradient.
Kelly L Whiteford, Heather A Kreft, Andrew J Oxenham
Human perceptual sensitivity to frequency modulation across the hearing range can be explained by a unitary neural code based on neural responses to amplitude modulation and fidelity of cochlear tuning.
Imaging of energy status and autophagy during neuronal migration revealed that ATP/ADP levels dynamically change during the migratory and stationary phases and that ATP reduction induces autophagy to maintain migration.
