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Wnts can act synergistically to affect G2 arrest via transcriptional upregulation of a Checkpoint Kinase in the absence of any detectable DNA damage.

Modulation of the energy barrier for membrane fusion is a common mechanism by which sensors in the synapse produce supralinear calcium dependence of vesicle release and short-term synaptic potentiation.

An optimization principle allows natural-image data to predict human sensitivity to synthetic, un-natural textures with multiple gray levels.

The orbitofrontal cortex is necessary for learning about value-neutral sensory associations to impact subsequent model-based behavior.

Sufficient aspartate drives specialization within a microbial colony, when some cells use it to create a limited carbon-resource, while other cells consume this resource and use aspartate for nucleotide synthesis.

A novel mode of oxygen delivery facilitated the adaptive evolution of vision in teleost fishes.

The switch from ubiquinone to rhodoquinone synthesis that is required for parasitic helminths to survive in anaerobic host tissues is due to alternative splicing of polyprenyltransferase COQ-2.

LARP4 protects mRNAs against deadenylation over a wide range of poly(A) lengths but with most apparent functional impact on short lengths known to sensitize PABP binding and mRNA stability.

The in-depth structural and functional work provide a deeper understanding as to how the epithelial sodium channel is a heteromeric ion channel that is regulated by Na⁺ and proteolysis.

Purinergic keratinocyte-to-sensory neuron signaling is a ubiquitous amplification mechanism that is required for normal mechanical, cold, and heat sensation in vivo.