Browse our Research Articles

Page 18 of 1,462
    1. Developmental Biology

    Extracellular adenosine deamination primes tip organizer development in Dictyostelium

    Pavani Hathi, Baskar Ramamurthy
    Extracellular adenosine deamination by ADGF generates ammonia that directs tip organizer development, revealing a conserved metabolic mechanism linking nucleotide turnover to developmental regulation.
    1. Neuroscience

    On CA1 ripple oscillations in rats and the reassessment of asynchronicity evidence

    Robson Scheffer-Teixeira, Adriano BL Tort
    Ripples maintain time-locked occurrence across the septo-temporal axis and hemispheres while showing local phase coupling, revealing a dual mode of synchrony in CA1 network dynamics.
    1. Microbiology and Infectious Disease

    An in vitro human vessel model to study Neisseria meningitidis colonization and vascular damages

    Léa Pinon, Melanie Chabaud ... Guilllaume Dumenil
    A vessel on a chip microfluidic device recapitulates the main features of meningococcal vascular colonization, providing high time and space microscopy resolution of the infection process in 3D.
    1. Plant Biology

    An increase of NPY1 expression leads to inhibitory phosphorylation of PIN-FORMED (PIN) proteins and suppression of pinoid (pid) null mutants

    Michael Mudgett, Zhouxin Shen ... Yunde Zhao
    A cause and impact of PIN-FORMED protein phosphorylation has been revealed.
    1. Immunology and Inflammation

    Immunoglobulin M regulates airway hyperresponsiveness independent of T helper 2 allergic inflammation

    Sabelo Hadebe, Anca Flavia Savulescu ... Frank Brombacher
    Immunoglobulin M has other functions beyond antibody class switching that have implications in asthma treatment.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Exploiting fluctuations in gene expression to detect causal interactions between genes

    Euan Joly-Smith, Mir Mikdad Talpur ... Andreas Hilfinger
    Analyzing stochastic cell-to-cell variability can potentially reveal causal interactions in gene regulatory networks.
    1. Physics of Living Systems

    Postural adaptations may contribute to the unique locomotor energetics seen in hopping kangaroos

    Lauren Thornton, Taylor Dick ... Christofer J Clemente
    Postural adjustments that reduce ankle leverage in kangaroos enhance tendon stress and elastic energy storage at higher speeds, providing energetic efficiency during hopping but potentially constraining the maximum size achievable by large species.
    1. Cell Biology

    The fate of pyruvate dictates cell growth by modulating cellular redox potential

    Ashish G Toshniwal, Geanette Lam ... Jared Rutter
    Pyruvate dictates redox balance and cell size, establishing metabolism as a dominant regulator of cellular fitness, unveiling new strategies to modulate cancer, regeneration, and diabetes.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Lifestyles shape genome size and gene content in fungal pathogens

    Anna Fijarczyk, Pauline Hessenauer ... Christian R Landry
    A genomic analysis shows that the evolution of genome size and gene content among fungal pathogens in the class Sordariomycetes varies depending on their interactions with hosts and vectors.
    1. Cancer Biology

    Endoscopic liquid biopsies of gastric fluid in a large human patient cohort reveal DNA content as a candidate tumor biomarker in gastric cancer

    Francine C Cadoná, Thais F Bartelli ... Emmanuel Dias-Neto
    Elevated gfDNA supports gastric cancer diagnosis and may guide management when combined with tissue biopsies, and in established cancer, higher gfDNA may predict better outcomes, potentially indicating immune-cell infiltration.