Browse our Research Articles

In vitro reconstitution identifies how lysosome-related vacuoles coordinate the synthesis and turnover of inorganic polyphosphates to create a powerful buffer system stabilising a vital metabolic parameter, the cytosolic concentration of phosphate.

A pharmacogenetic approach provides a foundational dataset describing the influence of opioids on synaptic processing in a brain microcircuit known to be critical for driving hedonic behaviors.

By providing new ways to map cortico-subcortical connectivity patterns, the proposed cross-species tractography approaches directly allow novel comparative studies between the human and macaque brain and enable subsequent explorations of brain-behaviour/disease symptom associations across individuals.

Restitution of RAP2A, human homolog of Drosophila asymmetric cell division regulator Rap2l, in glioblastoma neurosphere cultures targets the stemness of glioblastoma stem cells and could contribute to reduce glioblastoma expansion.

Expectation optimizes perception through center-surround inhibition, enhancing expected representations while suppressing similar, irrelevant ones.

The enteric bacterial Shigella secretes a virulence factor that degrades the pivotal human defense protein RNF213, thereby protecting cytosolic bacteria from interferon-driven ubiquitylation and associated innate immunity.

RAB27A-dependent mitochondrial recruitment of SYTL5 promotes mitophagy and mitochondrial bioenergetics upon hypoxia.

Novel function of Prosapip1, a scaffolding protein highly expressed in the hippocampus, in maintaining postsynaptic density integrity and plays a vital role in synaptic plasticity, learning, and memory.

Mitochondrial remodeling, ROS-dependent signaling, and diverse environmental and physiological cues underlie the initiation and persistence of locomotory activity of C. elegans in toxic H₂S.