Vikram Chandra, Samantha Elizabeth Tseng ... Mansi Srivastava
Studying the reproductive life history of an acoel reveals that a body-size-dependent program regulates organ growth and regeneration dynamics and discovers a novel form of egg-laying behavior.
Unique extracellular vesicle microRNA signatures resulting from G protein-coupled receptor activation indicate distinct downstream signaling and functional networks by receptor, with implications for developing new drugs and understanding their long-term and off-target effects.
Inactivation of beta 1,4-galactosyltransferase 1 leads to enhanced T-cell receptor activation and CD8+ T-cell function by affecting the galactosylation of T-cell receptor and CD8.
Mycobacterium tuberculosis utilizes nucleomodulins to disrupt host inflammatory responses and lysosomal maturation, uncovering a novel strategy for immune evasion and intracellular survival.
Profiling endogenous Bruchpilot proteins in multiple cell types in mushroom bodies uncovered multilayered spatial configurations of active zones, from stereotyped intracellular distribution patterns to local arrangements of neighboring synapses.
Manuel Dominguez-Rodrigo, Enrique Baquedano ... Audax Mabulla
The discovery of the earliest direct evidence of systematic proboscidean butchery at Olduvai Gorge demonstrates that by 1.8 Ma early hominins had strategically integrated megafaunal exploitation into their subsistence systems.
Functional connectivity reveals brain attractors that match predictions of free‑energy‑minimizing attractor theory, yielding an interpretable generative model of brain dynamics in rest, task, and disease.
