The retrieval-extinction paradigm elicits a short-term fear amnesia that differs in cue specificity, timescale, and dependence on thought-control ability from the long-term amnesia believed to be associated with memory reconsolidation.
An integrative analysis of scRNA-seq and spatial transcriptomics provides complementary views into the biology of pre-clinical colorectal cancer models in mice with possible applications to the human system.
Catherine Sirois-Delisle, Susan CC Gordon, Jeremy Kerr
Across continents, half of odonate species shifted both ranges and phenologies in response to climate warming, with southern species and those experiencing less temperature variability shifting ranges more strongly.
Alkis M Hadjiosif, Kahori Kita ... John W Krakauer
Patients with stroke often show impairment in both moving and holding the arm, deficits that are dissociable experimentally, suggesting that moving and holding are controlled by separate neural mechanisms.
Austin Tedman, John A Olson III ... Jonathan P Schlebach
Combining deep mutational scanning with CRISPR, interactome measurements, and electrophysiology reveals nuanced effects of the lectin chaperone calnexin on the pharmacological properties of 232 cystic fibrosis variants.
Tanja Nielsen, Anaïs Kervadec ... Alexandre R Colas
Cross-species functional genomics identify ribosomal protein genes as key regulators of cardiomyocyte proliferation and heart development, implicating them as candidate modifiers for HLHS and revealing new avenues for therapeutic discovery.
