A conserved neuropeptidergic circuit directly links internal glucose levels to sweet taste sensitivity, providing a central mechanism for coupling metabolic state to feeding behavior.
Theoretical and computational analyses demonstrate that cell intercalation within epithelial cell layers is analogous to the unbinding of topological defects in hexatic liquid crystals, offering a framework for calculating cellular forces and velocities during collective migration.
Allocating space, materials and energy to an eye's optics and photoreceptor array is a major factor in eye design that explains obvious differences between simple eyes and compound eyes.
Residual plasma from rapid routine clinical chemistry tubes enables cell-free DNA NGS-based analysis, providing an untapped, scalable, and accessible resource without specialized collection workflows.
RadD recognition by NKp46 converts Fusobacterium nucleatum from an immune-evasive pathogen into a trigger of natural killer cell-mediated tumor control in a context-dependent manner.
Chengcheng Fan, Alexander A Cohen ... Magnus AG Hoffmann
Bivalent EABR mRNA boosters broaden neutralizing responses to Omicron subvariants by promoting diverse receptor-binding domain epitope targeting, although antibody responses remain partially shaped by immune imprinting from prior vaccination.
During convergent extension morphogenesis, non-canonical Wnt induces the signal transducer Dishevelled to transition from Vangl to Frizzled, a process that is inhibited by Prickle but facilitated by the co-receptor Ror.
An on-demand seizure model in chronically epileptic mice integrates reliability and etiological relevance, providing a mechanistically grounded, efficient platform for evaluating pharmacological interventions.
