Systematic characterization of terminating ribosomes uncovers sequence features influencing ribosome dynamics at stop codons with direct implications in 3' UTR translation.
Nickase and nuclease Prime Editors offer complementary routes for precise zebrafish genome editing, balancing accuracy for substitutions with efficiency for short insertions.
Rochelle M Shih, Yasuhiro Arimura ... Hironori Funabiki
DNA methylation suppresses H2A.Z deposition by inhibiting recruitment of the chaperone SRCAP, while the structural study suggests that methylated DNA can make the H2A.Z nucleosome slightly more accessible.
Although auditory encoding of music is robust early in infancy, the transformation of this input into movement patterns develops substantially over the first postnatal year, without reaching full maturity.
Gaseous CO2 acts as a neuron to glia messenger in peripheral myelin to trigger opening of Schwann Cell Cx32 hemichannels in response to axonal action potential propagation.
Elin Larsson, Aleksei Kabedev ... Richard Lundmark
Membrane insertion of Dyngo-4a results in a dynamin-independent inhibition of caveola dynamics, revealing that outer leaflet lipid packing in the plasma membrane contributes to the confinement of caveolae.