Browse our Research Articles

Page 3 of 1,459
    1. Neuroscience

    Human brain dynamics and spatiotemporal trajectories during threat processing

    Joyneel Misra, Luiz Pessoa
    Intrinsic neural attractors and extrinsic environmental inputs jointly steer the dynamic trajectories of brain activity during threat processing.
    1. Evolutionary Biology

    Accelerated evolution in networked metapopulations of Pseudomonas aeruginosa

    Partha Pratim Chakraborty, Rees Kassen
    Centralized migration accelerates adaptation and drives parallel evolution, emphasizing the key influence of spatial organization on evolutionary dynamics across systems from pathogen transmission to species range shifts.
    1. Physics of Living Systems

    Feeding rates in sessile versus motile ciliates are hydrodynamically equivalent

    Jingyi Liu, Yi Man ... Eva Kanso
    Fluid flow analysis reveals that both swimming and sessile ciliates achieve competitive nutrient uptake, resolving the long-standing debate over the hydrodynamic advantage of either strategy.
    1. Microbiology and Infectious Disease

    Mast cells promote pathology and susceptibility in tuberculosis

    Ananya Gupta, Vibha Taneja ... Shabaana A Khader
    Conserved mast-cell activation, marked by elevated protease expression, aligns with progressive tuberculosis across human, macaque, and murine models.
    1. Neuroscience

    Identifying regulators of associative learning using a protein-labelling approach in Caenorhabditis elegans

    Aelon Rahmani, Anna McMillen ... Yee Lian Chew
    An innovative and scalable proximity labelling method profiled proteins present in the Caenorhabditis elegans brain during learning, identifying known regulators as well as novel biological pathways.
    1. Epidemiology and Global Health

    Global risk mapping of highly pathogenic avian influenza H5N1 and H5Nx in the light of epidemic episodes occurring from 2020 onwards

    Marie-Cécile Dupas, Maria F Vincenti-Gonzalez ... Simon Dellicour
    Post-2020, highly pathogenic avian influenza H5 circulation is characterised by spatially expanded ecological suitability, changes in key environmental predictors, and a wider range of avian species affected.
    1. Neuroscience

    Executive resources shape the impact of language predictability across the adult lifespan

    Merle Marie Schuckart, Sandra Martin ... Jonas Obleser
    Analyses of self-paced reading times reveal that linguistic prediction deteriorates under limited executive resources, with this resource sensitivity becoming markedly more pronounced with advancing age.
    1. Structural Biology and Molecular Biophysics

    Allosteric effects of the coupling cation in melibiose transporter MelB

    Parameswaran Hariharan, Yuqi Shi ... Lan Guan
    Intrinsic conformational flexibility of a solute transporter is restrained by substrates, resulting in Na+ allosterically enhancing primary substrate binding through cooperative constraints on the dynamics of the cytoplasmic inner barrier.
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty acyltransferase

    Wenjie W Zeng, Garrison Komaniecki ... Yuxin Mao
    A novel F-actin-binding motif consisting of an α-helix hairpin from a Legionella pneumophila lysine fatty acyltransferase has the potential to be developed as an F-actin probe.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

    Abdulkadir Ozkan, Hari K Padmanabhan ... Jeffrey D Macklis
    Developmentally-based directed differentiation from cortical progenitors sets a foundation for in vitro mechanistic and therapeutic disease modeling, and toward regenerative neuronal repopulation and circuit repair.