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BOAS is a platform for building multivalent viral protein immunogens without a scaffold, such as a nanoparticle, to elicit broad influenza vaccine responses.

Holographic neuronal stimulation shows that auditory cortex neurons with shared functional properties rapidly adjust their responses during sensory processing, revealing a circuit-level mechanism that regulates overall network activity balance.

Theoretical and computational modeling reveals a mechanism of active patterning of uniform isotropic actin gels into dense nematic bundles, providing a physical basis for the adaptability of the actin cytoskeleton.

Children show less robust memory retention overnight and after 2 weeks, with memories transforming more rapidly from detailed to gist-like neural representations, revealing less stable consolidation mechanisms than in adults.

Quantitative Drosophila pupal wing experiments support planar polarity depending on cell-scale signalling that does not involve depletion of a limited pool of core proteins or polarised transport on microtubules.

Critical differences in how the BNST responds to different types of fear across male and female mice.

Cryo-EM and electrophysiology reveal the mechanism of SK2 channel modulation by the bee toxin apamin and small molecules, providing insights that enable the rational design of targeted SK2 channel therapeutics.

Songbird HVC sequences arise from a balance of ionic currents and structured inhibition, providing a mechanistic framework for understanding cortical sequence generation.

Sub-surface imaging demonstrates that vertical shear beneath fingertip ridges enables high mechanical spatial resolution to support tactile sensing.

Reducing vaccine development time from 12 months to 6 reduces forecasting error by 25%, while reducing lags in genome sequence submission reduces uncertainty of current clade frequencies by 50%.