Microfossils reported from Archaean BIFs most likely were liposome-like protocells, which had evolved intracellular mechanisms for energy conservation but not for regulating cell morphology and replication.
Adam A Atanas, Alicia Kun-Yang Lu ... Steven W Flavell
New machine vision tools are used to align densely packed cells recorded from live, deforming tissues and automatically annotate the identities of the recorded cell types.
A detailed annotation of anatomical brain structures (some novel) of the spider Uloborus diversus is provided based on a three-dimensional immunostain atlas.
Jean-Mathieu Desveaux, Eric Faudry ... Pascal Poignard
Human antibodies isolated from cystic fibrosis patients against PscF and PcrV of the Pseudomonas aeruginosa Type 3 Secretion System reveal that anti-PcrV antibodies inhibit secretion through distinct mechanisms.
Volume EM and connectome reconstruction of the apical organ of a ctenophore combined with high-speed imaging reveals a neuronal coordination of balancer cilia in the gravisensory organ.
A threefold hippocampal code across conceptual directions, phase-locked to entorhinal grid activity, reveals a periodic mechanism through which entorhinal grids structure hippocampal vector representations.
Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from totipotency and ensure preimplantation development.
Maryanne Derkaloustian, Pushpita Bhattacharyya ... Charles B Dhong
To study fine touch, selecting samples based on how many mechanical instabilities they can form is more predictive than using the friction coefficient, which has been the default choice.