Browse our Research Articles

Multi-omics investigation identifies cell-type JAK-STAT heterogeneity as a predictive biomarker for PD-1 blockade in breast cancer.

A saw-like proboscis, forceful pulling movements, and precise targeting of softer skin sites allow tsetse flies to draw blood from remarkably diverse vertebrate hosts.

Passive recordings miss patterns of brain activity that fade before they can be observed, but perturbations designed to re-excite those patterns make estimates of neural connections far more accurate.

Systematic dissection of Rab GTPase function in developing neurons reveals that early and recycling endosome-associated Rabs regulate largely distinct aspects of neuronal morphogenesis and circuit assembly across developmental time.

Computational and theoretical analyses reveal that Caenorhabditis elegans whole-brain activity can be represented in an 8-dimensional hyperbolic manifold that hierarchically links sensory ON/OFF inputs to motor states, providing a compact geometric framework for how a nervous system processes sensory information.

Sci-L3-Strand-seq uncovers sister chromatid exchange as a frequent hidden outcome of Cas9-induced breaks, revealing genome-editing consequences that are invisible to conventional sequencing, and can be associated with structural variations.

Co-folding methods accurately place and rank ligands within an optimization series, yet fail to separate true binders from docking false positives, suggesting complementary roles in drug discovery.

Low-frequency depression, an understudied form of synaptic plasticity, is proposed to reflect a reorganization of synaptic vesicles inside the readily releasable pool.

Resting-state MEG reveals a replicable, full-frequency profile of ageing that offers a foundation for comparing and validating brain health biomarkers although detecting specific effects requires careful consideration of statistical power.

Glutamine drives its own synthetase to assemble into inhibitory filaments, linking product concentration directly to a conformational switch that gates the active site.