Browse our Research Articles

Working memory alternates between remembered items in a rhythmic theta cycle.

The yeast mitochondrial malate dehydrogenase–citrate synthase metabolon is a dynamic multienzyme complex that continuously assembles and disassembles in response to respiratory activity, mitochondrial matrix pH, and substrate abundances.

Stable allele-specific epigenetic regulation creates cellular mosaicism of numerous autosomal dosage-sensitive genes involved in human neurological and developmental disorders.

Lenacapavir disrupts HIV-1 capsid elasticity, inducing mechanical rupture at the nuclear pore, highlighting that altering viral material properties can be a viable antiviral drug design strategy.

Regulatory immune cells accumulate at the nose-to-brain interface during neuroinflammation, potentially dampening damaging immune responses.

Systematic characterization of terminating ribosomes uncovers sequence features influencing ribosome dynamics at stop codons with direct implications in 3' UTR translation.

The brain uses separate prediction error and prediction uncertainty signals to trigger event boundaries.

DNA methylation suppresses H2A.Z deposition by inhibiting recruitment of the chaperone SRCAP, while the structural study suggests that methylated DNA can make the H2A.Z nucleosome slightly more accessible.

Although auditory encoding of music is robust early in infancy, the transformation of this input into movement patterns develops substantially over the first postnatal year, without reaching full maturity.

A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure.