Browse our Research Articles

Membrane composition modulates EGFR conformational dynamics and signaling, revealing that the bilayer properties can override ligand control to influence receptor activation in health and disease.

Environmental differences alter behavioral performance in Drosophila melanogaster without eliminating consistent individual differences.

Sensory cues increase risky choice when paired with wins but reduce risky choice when paired with losses, with parallel shifts in sensitivity to negative outcomes.

Inhibitor of κB kinase signalling differentially controls development and survival of γδ T cell subsets through nuclear factor-κB activation and repression of receptor-interacting protein kinase 1-driven necroptosis, revealing distinct inflammatory signalling requirements from αβ T cells.

Spinal translational control mechanisms regulate gene expression and nociceptive circuit sensitization during the chronic phase of neuropathic pain.

The ability to predict brain activity from words before they occur can be explained by information shared between neighbouring words, without requiring next-word prediction by the brain.

Principles of weakly coupled oscillators capture human figure-ground segregation and its training-induced enhancement, indicating gamma synchrony remains a plausible grouping mechanism.

Genetic and biochemical analyses show that loss of the E3 ubiquitin ligases ZNRF3 and RNF43 enhances EGFR signaling by impairing EGFR ubiquitination and degradation, revealing a new cancer-promoting mechanism.

Mechanosensitive recruitment of DLC1 to focal adhesions creates a positive feedback loop that locally amplifies Rho activation in response to tension.