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DuoHexaBody‑CD37 triggers complement‑independent cytotoxic signaling in diffuse large B-cell lymphoma (DLBCL), revealing therapeutic pathways that can be exploited to enhance tumor cell killing through targeted combination strategies.

Poor paternal nutrition at the time of conception shapes post-fertilisation developmental trajectory, fetal growth, and placental dynamics.

Although physical exercise could be a beneficial protective factor for brain health in later life, older adults tend to overestimate their actual levels of activity.

Early-life malaria exposure leaves a durable immunological imprint associated with reduced antibody responses to unrelated infections and vaccines.

Computer-Aided Aptamer Modeling and Optimization (CAAMO) enables structure-guided RNA aptamer affinity maturation, producing a SARS-CoV-2 RBD (receptor binding domain) binder that rivals neutralizing antibodies and retains predicted activity across variants.

Tetrahymena germline chromosome ends contain germline-limited sequences that are removed by chromosome breakage, a critical step for programmed DNA elimination of other germline-limited sequences and successful sexual reproduction.

Extrachromosomal circular DNA has been identified as a novel component of stress granule cores, indicating its essential involvement in eukaryotic stress response pathways at the level of protein synthesis.

The in vitro experiments that used the artificial genetic codes tested here did not provide support for the error minimization theory.

The cerebellum and ventral tegmental area interact during unexpected omissions of aversive outcomes in humans, supporting a role for reward-like prediction error signaling in fear extinction learning.

ACC contains specialized neurons that sustain rich action-relevant information after action execution, enabling prolonged action monitoring, and supporting complex associative linking across events.