Simar Pal Singh, Kumar Mangalam ... Annemiek B van Spriel
DuoHexaBody‑CD37 triggers complement‑independent cytotoxic signaling in diffuse large B-cell lymphoma (DLBCL), revealing therapeutic pathways that can be exploited to enhance tumor cell killing through targeted combination strategies.
Massimiliano Semeraro, Giuseppe Negro ... Davide Marenduzzo
In a polymer model of chromatin that explicitly incorporates different types of transcription factors, both specialised and mixed factories emerge naturally, with their composition governed by their size.
RNA differentially regulates the assembly pathways of bacterial and host α-helical peptides, revealing supramolecular architecture as a tunable determinant of cytotoxic and antimicrobial function.
A single temporal integration process links momentary perceptual biases to the generalization of learned skills, providing a unifying account of specificity versus flexibility in human learning.
Reducing vertical forces reveals kinesin-1 as a robust motor capable of sustaining high loads and efficiently generating large collective forces with multiple motors.
Han SJ Cheong, Katharina Eichler ... Gwyneth M Card
Circuit analyses of synaptic connectivity in networks connecting descending and motor neurons in the Drosophila Male Adult Nerve Cord connectome reveal the modular network organization of descending to motor pathways.
The loss of FMRP does not affect how neuronal ribosomes are stalled or where they are stalled, but reduces the number of neuronal RNA granules that contain stalled ribosomes.