Microfossils reported from Archaean BIFs most likely were liposome-like protocells, which had evolved intracellular mechanisms for energy conservation but not for regulating cell morphology and replication.
Volume EM and connectome reconstruction of the apical organ of a ctenophore combined with high-speed imaging reveals a neuronal coordination of balancer cilia in the gravisensory organ.
Adam A Atanas, Alicia Kun-Yang Lu ... Steven W Flavell
New machine vision tools are used to align densely packed cells recorded from live, deforming tissues and automatically annotate the identities of the recorded cell types.
Jean-Mathieu Desveaux, Eric Faudry ... Pascal Poignard
Human antibodies isolated from cystic fibrosis patients against PscF and PcrV of the Pseudomonas aeruginosa Type 3 Secretion System reveal that anti-PcrV antibodies inhibit secretion through distinct mechanisms.
Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from totipotency and ensure preimplantation development.
Maryanne Derkaloustian, Pushpita Bhattacharyya ... Charles B Dhong
To study fine touch, selecting samples based on how many mechanical instabilities they can form is more predictive than using the friction coefficient, which has been the default choice.
Premature termination of transcription influences ribosomal RNA output and RNA polymerase I drug sensitivity, revealing a mechanism of resistance to transcription-targeting chemotherapy.
