Browse our Research Articles

Page 3 of 1,485
    1. Ecology
    2. Evolutionary Biology

    Rapid riparian ecosystem recovery in low-latitudinal North China following the end-Permian mass extinction

    Wenwei Guo, Li Tian ... Jinnan Tong
    In low-latitude North China, riparian ecosystems began to recover 2–3 million years after the end-Permian mass extinction.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Redirection of SARS-CoV-2 to phagocytes by intranasal sACE2-Fc as a universal decoy confers complete prophylactic protection

    Jingyi Wang, Jiangchuan Li ... Bo Feng
    Functional and mechanistic analyses reveal that intranasal decoys engage phagocytic clearance beyond viral neutralization to provide effective protection, establishing immune redirection for developing broad-spectrum countermeasures against airborne viral threats.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Adrenomedullin restores the human cortical interneurons migration defects induced by hypoxia

    Alyssa Puno, Wojciech P Michno ... Anca M Pasca
    Exposure of human cortical interneurons to hypoxia leads to decreased migration, a process that is likely altered in preterm infants and contributes to the increased risk for neurodevelopmental problems.
    1. Cancer Biology
    2. Developmental Biology

    Tumors mimic the niche to inhibit neighboring stem cell differentiation

    Yang Zhang, Yuejia Wang ... Shaowei Zhao
    Drosophila female germline tumors mutant for bam or bgcn mimic the stem cell niche to inhibit the differentiation of neighboring wild-type germline stem cells.
    1. Neuroscience

    Bilateral equalization of synaptic output in olfactory glomeruli of Xenopus tadpoles

    Marta Casas, Beatrice Terni, Artur Llobet
    A novel bilateral compensatory mechanism important for the activity of olfactory glomeruli in Xenopus tropicalis tadpoles was uncovered.
    1. Biochemistry and Chemical Biology

    The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells

    Guillaume Lefrançois, Emilie Lavallée ... Gerardo Ferbeyre
    Biochemical and genetic evidence identifies ATP5I as a biguanide target, redefining biguanide action through ATP synthase regulation and assembly, mitochondrial architecture, and mitochondrial protein turnover.
    1. Genetics and Genomics

    Stranded short nascent strand sequencing reveals the topology of DNA replication origins in Trypanosoma brucei

    Slavica Stanojcic, Bridlin Barckmann ... Yvon Sterkers
    Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide composition, G‑quadruplex enrichment, and distinctive nucleosome patterns.
    1. Neuroscience

    Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing

    Katrina Bartas, Pieter Derdeyn ... Kevin T Beier
    Addictive drugs, as well as ketamine/xylazine, change the connectivity to ventral tegmental area dopamine cells, which may be related to cellular activity.
    1. Neuroscience

    Subregional activity in the dentate gyrus is amplified during elevated cognitive demands

    Charlotte CM Castillon, Shintaro Otsuka ... Anis Contractor
    Selective engagement of suprapyramidal dentate gyrus neurons during a high-demand pattern separation task reveals blade-specific circuit engagement for enhancing mnemonic discrimination.
    1. Chromosomes and Gene Expression

    Identification of the regulatory elements and protein substrates of lysine acetoacetylation

    Qianyun Fu, Terry Nguyen ... Y George Zheng
    A newly developed chemo-immunological strategy enabled detection of acetoacetate-mediated lysine acetoacetylation, identified the associated regulatory enzymes, and revealed its distinct biological functions and physiological significance.