Browse our Research Articles

Analysis of inositol pyrophosphate dynamics upon inorganic phosphate (P_i) starvation identifies 1,5-IP₈ as the inositol pyrophosphate isomer signaling P_i sufficiency to the SPX domain of Pho81 that controls the transcriptional P_i starvation program.

A novel analytical workflow to quantitatively track motions of thousands of nucleosomes within chromatin fibers by high-speed atomic force microscopy.

PLWH over a decade of ART showed a significant reshaping of the function and expression of inhibitory receptors across the CD8+ T cell landscape, ultimately leading to a decrease of CD107a TIGIT HIV-1-specific CD8+ T cells recovered by TIGIT blockade.

LIM-homeodomain transcription factor Lmx1a co-regulates multiple developmental processes in the cortical hem, a major signaling center necessary for hippocampus formation in the mammalian brain.

Identification of human DNA sites differentially methylated with aging across six different primary immune cells suggests that the sensing of hypoxia drives the epigenetic clock.

The frequency content of resting-state fMRI signals contains information that can characterize and predict local variations in hemodynamic response timing which enhances the temporal precision of fMRI.

Gene function studies confirmed that the BATF-PD1 axis and BATF-IL27 axis are regulatory factor for lipid accumulation in hepatocytes and adipocytes.

Analysis of data from monozygotic twins reveals that DNA methylation level in human blood cells is reactive to cigarette smoking.

Genome-scale integration of transposon mutagenesis with a redox biosensor identified a hypothetical transcription factor- Rv0158 required to calibrate the growth, cytoplasmic redox potential, and respiration of Mycobacterium tuberculosis in response to metabolic switching from glucose to fatty acids.

Characterization of an extra-membrane site in I_Ks formed by KCNQ1 S1, Pore and S6 domains and the near extracellular region of KCNE1, which forms a binding pocket for channel activators.