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The infection of T helper lymphocytes by SARS-CoV-2, mediated via the CD4 molecule, alters cellular function and enhances expression of the anti-inflammatory cytokine IL-10, potentially impairing immune response in individuals with COVID-19.

Human infants can use various muscle activations as soon as birth to produce rhythmic leg movements, but the strategy underlying this variable output seems to change between the first months of life and toddlerhood.

Nucleosomes inside of baker’s yeast cells largely do not resemble those found in test tubes.

Embryo-derived TNF promotes CPLA_2α phosphorylation and arachidonic acid release from luminal epithelium to induce fibroblast activation and decidualization.

Inflammation reprograms the citrate cycle in adrenocortical cells leading to altered steroidogenesis.

Multimodal spectroscopy (smFRET, EPR, SAXS, and SANS) and integrative structural modeling reveal large-scale domain rearrangements in human guanylate binding protein 1 (hGBP1) that are driving forces for the formation of oligomers that enable its biological function in innate immune defense.

Gαq stimulates HDAC5 phosphorylation by PKC-independent PKD/PKCμ activation to induce the IκB expression and limit the NF-κB-mediated inflammatory response which essential for proper endometrial decidualization and early pregnancy.

There was substantial change in primary care activity following the onset of the COVID-19 pandemic in March 2019 as indicated by key measures reflective of clinical activity in general practice but service was largely restored by April 2021.

Analysis of 458 Kalinago provides new insights into the population's genetic structure, the contribution of Native American ancestry to skin pigmentation, and the identification of a coding variant in OCA2 with an estimated –8 melanin units effect size.

Dimensionality reduction techniques reveal how the organization of neurotransmitter receptor and transporter co-expression in the human brain may bridge the gap between brain structure and function.