Browse our Research Articles

Page 260 of 1,418
    1. Developmental Biology
    2. Evolutionary Biology

    Coronary artery established through amniote evolution

    Kaoru Mizukami, Hiroki Higashiyama ... Hiroki Kurihara
    During the evolution of amniotes, the transformation of branchial arches coincided with the drastic remodeling of the ancestral extrinsic cardiac arteries, giving rise to novel ventricular coronary arteries that are unique to amniotes.
    1. Neuroscience

    Functional imaging of conduction dynamics in cortical and spinal axons

    Milos Radivojevic, Anna Rostedt Punga
    Reconstruction of axonal morphologies based on extracellular action potentials enables label-free electrical visualization of axonal conduction trajectories, providing a noninvasive method for functional profiling of cortical and spinal axons.
    1. Genetics and Genomics

    Ether lipid biosynthesis promotes lifespan extension and enables diverse pro-longevity paradigms in Caenorhabditis elegans

    Lucydalila Cedillo, Fasih M Ahsan ... Alexander A Soukas
    Increased production of ether lipids is required to extend lifespan in response to metformin, phenformin, and multiple, distinct, longevity-promoting manipulations, illuminating the possibility that raising ether lipid levels represents a new therapeutic strategy to support healthy aging.
    1. Microbiology and Infectious Disease

    Environmental pH signals the release of monosaccharides from cell wall in coral symbiotic alga

    Yuu Ishii, Hironori Ishii ... Shinichiro Maruyama
    Coral symbiotic alga is capable of degrading the own cell wall components by cellulase-related enzymes and releasing sugars as a simple and autonomous environmental response, even when the host-derived signals are not present.
    1. Neuroscience

    Gaze patterns and brain activations in humans and marmosets in the Frith-Happé theory-of-mind animation task

    Audrey Dureux, Alessandro Zanini ... Stefan Everling
    Shared traits in gaze patterns and brain activations between marmosets and humans during Theory of Mind animations reveal cross-species cognitive similarities.
    1. Ecology
    2. Genetics and Genomics

    Decoding the genetic and chemical basis of sexual attractiveness in parasitic wasps

    Weizhao Sun, Michelle Ina Lange ... Jan Buellesbach
    How biologically relevant chemical information can be genetically maintained and conveyed in complex sex pheromonal profiles.
    1. Evolutionary Biology
    2. Neuroscience

    A brain-wide analysis maps structural evolution to distinct anatomical module

    Robert A Kozol, Andrew J Conith ... Erik R Duboue
    Genetic analyses reveal that neuroanatomical areas that are developmentally related co-evolve with one another.
    1. Cell Biology

    Cas phosphorylation regulates focal adhesion assembly

    Saurav Kumar, Amanda Stainer ... Jonathan A Cooper
    A novel two-step model for integrin activation primed by Cas during cell migration and spreading on multiple extracellular matrix ligands.
    1. Computational and Systems Biology
    2. Neuroscience

    High-resolution volumetric imaging constrains compartmental models to explore synaptic integration and temporal processing by cochlear nucleus globular bushy cells

    George A Spirou, Matthew Kersting ... Paul B Manis
    Volume electron-microscopic reconstructions of auditory brainstem neurons and their afferent synapses were used to develop a pipeline creating biophysically defined computational models with heterogenous inputs, revealing roles for subthreshold synapses to enhance temporal processing unique features of their dendrites.
    1. Cell Biology

    A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression

    Chaojun Yan, Jingjing Xiong ... Jing Zhang
    Molecular biology experiments identified a cleaved METTL3, which mediates the METTL3–METTL3 interaction, a prerequisite step for recruitment of WTAP in MTC assembly, controlling m6A deposition and cancer progression.