Browse our Research Articles

Page 380 of 1,392
    1. Neuroscience

    Molecular characteristics and laminar distribution of prefrontal neurons projecting to the mesolimbic system

    Ákos Babiczky, Ferenc Matyas
    Molecular, laminar, and regional characterization in combination with classical and conditional tracing techniques reveal that medial prefrontal cortical neurons innervating the nucleus accumbens and the ventral tegmental area form distinct populations.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Multiple ciliary localization signals control INPP5E ciliary targeting

    Dario Cilleros-Rodriguez, Raquel Martin-Morales ... Francesc R Garcia-Gonzalo
    Four conserved ciliary localization signals in the Joubert syndrome-associated INPP5E phosphoinositide phosphatase control its ciliary accumulation.
    1. Computational and Systems Biology

    Quantifying dynamic facial expressions under naturalistic conditions

    Jayson Jeganathan, Megan Campbell ... Michael Breakspear
    A novel computational pipeline uses time-frequency analysis to capture the dynamics of human facial expressions, and demonstrates abnormal facial dynamics in melancholic depression.
    1. Structural Biology and Molecular Biophysics

    Impact of energy limitations on function and resilience in long-wavelength Photosystem II

    Stefania Viola, William Roseby ... A William Rutherford
    Comparisons of enzyme efficiency and electron transfer show that, to oxidize water using lower energy light, the two types of far-red photosystem II have adopted opposite trade-offs between efficiency of light use and resilience to light damage.
    1. Cancer Biology
    2. Cell Biology

    EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation

    Ariel Pribluda, Anneleen Daemen ... Melissa R Junttila
    G9a regulates chromatin-bound b-catenin enabling cell-intrinsic control of WNT signaling-mediated cell fate decisions.
    1. Neuroscience

    Botulinum neurotoxin accurately separates tonic vs. phasic transmission and reveals heterosynaptic plasticity rules in Drosophila

    Yifu Han, Chun Chien ... Dion Dickman
    A new tool enables electrophysiological isolation of input-specific neurotransmission in a powerful model glutamatergic circuit.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A paternal bias in germline mutation is widespread in amniotes and can arise independently of cell division numbers

    Marc de Manuel, Felix L Wu, Molly Przeworski
    A paternal bias in germline mutation is seen throughout amniotes and may be explained by sex differences in DNA damage and repair after primordial germ cell specification.
    1. Genetics and Genomics

    Data-driven, participatory characterization of farmer varieties discloses teff breeding potential under current and future climates

    Aemiro Bezabih Woldeyohannes, Sessen Daniel Iohannes ... Matteo Dell'Acqua
    A genomic, climatic, agronomic, and participatory characterization of teff agrobiodiversity shows opportunities and challenges of teff improvement in the face of climate change.
    1. Microbiology and Infectious Disease

    Vaccination decreases the risk of influenza A virus reassortment but not genetic variation in pigs

    Chong Li, Marie R Culhane ... Montserrat Torremorell
    Vaccination has the potential to decrease swine influenza diversification by restricting influenza virus co-infections and reassortment events in pigs.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    STAG2 promotes the myelination transcriptional program in oligodendrocytes

    Ningyan Cheng, Guanchen Li ... Hongtao Yu
    Brain-specific inactivation of cohesin-STAG2 in the mouse causes myelination defects, thus implicating hypomyelination as a contributing factor to cohesinopathy and establishing oligodendrocytes as a cell system to probe the physiological function of cohesin-mediated genome folding.