Browse our Research Articles

Page 413 of 1,393
    1. Neuroscience

    Different brain systems support learning from received and avoided pain during human pain-avoidance learning

    Marieke Jepma, Mathieu Roy ... Albert Dahan
    Pharmacological fMRI study provides evidence that learning from the unexpected presence and absence of pain is mediated by different brain systems.
    1. Developmental Biology
    2. Neuroscience

    Cross-modality synthesis of EM time series and live fluorescence imaging

    Anthony Santella, Irina Kolotuev ... Zhirong Bao
    A landmark-based cross-modality alignment method robust to variation in landmark sets is applied to annotate an EM time series of Caenorhabditis elegans embryonic development as a community resource.
    1. Cell Biology

    MAF1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass

    Ellen Phillips, Naseer Ahmad ... Deborah L Johnson
    Identification of a novel role for the transcriptional repressor, MAF1, and RNA polymerase III-dependent transcription, in osteoblast differentiation, mineralization, and bone biology.
    1. Epidemiology and Global Health

    Impact of the COVID-19 pandemic on breast cancer screening indicators in a Spanish population-based program: a cohort study

    Guillermo Bosch, Margarita Posso ... Francesc Macià
    The COVID-19 pandemic reduced participation in a Spanish population-based breast cancer screening program, especially among regular participants, while other outcomes like recall and cancer detection were not negatively affected by the interruption of screening.
    1. Neuroscience

    Cortical adaptation to sound reverberation

    Aleksandar Z Ivanov, Andrew J King ... Nicol S Harper
    The auditory system adapts to the changing acoustics of reverberant environments by temporally shifting the inhibitory tuning of cortical neurons to reduce the effects of reverberation.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37

    Piotr Kolesinski, Kuei-Chen Wang ... Partho Ghosh
    Streptococcus pyogenes M87 protein unfurls its coiled coil to capture and neutralize the human antimicrobial peptide LL-37.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Rapid adaptation of a complex trait during experimental evolution of Mycobacterium tuberculosis

    Tracy M Smith, Madison A Youngblom ... Caitlin S Pepperell
    Mycobacterium tuberculosis, which causes tuberculosis, can evolve rapidly in response to new environments by mutating genetic regulators that control multiple genes at once.
    1. Microbiology and Infectious Disease

    Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract

    Valérie Laroute, Catherine Beaufrand ... Muriel Cocaign-Bousquet
    Generally recognised as safe GABA-producing L. lactis strains could be considered as future therapeutic agents for the management of visceral pain and the anxious profile of IBS patients.
    1. Microbiology and Infectious Disease

    WhyD tailors surface polymers to prevent premature bacteriolysis and direct cell elongation in Streptococcus pneumoniae

    Josué Flores-Kim, Genevieve S Dobihal ... David Z Rudner
    Selective removal of Wall Teichoic Acids from the envelope of Streptococcus pneumoniae prevents bacteriolysis and directs zonal cell wall synthesis.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity

    Isabel Nocedal, Michael T Laub
    Ancestral reconstruction of a signaling pathway reveals the mutations responsible for producing specificity of the two paralogous pathways produced by a duplication event.