Browse our Research Articles

Page 414 of 1,393
    1. Neuroscience

    The control and training of single motor units in isometric tasks are constrained by a common input signal

    Mario Bräcklein, Deren Yusuf Barsakcioglu ... Dario Farina
    Humans trained to flexibly control individual motor units within a muscle do not naturally learn to gain control over recruitment order.
    1. Developmental Biology

    Amoeboid-like migration ensures correct horizontal cell layer formation in the developing vertebrate retina

    Rana Amini, Archit Bhatnagar ... Caren Norden
    Horizontal cell undergoes amoeboid-like migration in the developing vertebrate retina, a not previously reported migration mode in the central nervous system, that allows them to move within a densely packed tissue without predetermined paths.
    1. Microbiology and Infectious Disease

    NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes

    Clarisse Leseigneur, Laurent Boucontet ... Olivier Dussurget
    Staphylococcus aureus NAD kinase promotes infection by protecting bacteria from host antimicrobial defenses and by supporting production of major virulence factors.
    1. Physics of Living Systems

    The role of surface adhesion on the macroscopic wrinkling of biofilms

    Steffen Geisel, Eleonora Secchi, Jan Vermant
    The three-dimensional structure of bacterial biofilms is governed by a buckling-delamination process that is determined by basic physical parameter that allow us to predict and control the biofilm morphology.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Selection for infectivity profiles in slow and fast epidemics, and the rise of SARS-CoV-2 variants

    François Blanquart, Nathanaël Hozé ... Simon Cauchemez
    Selection acting on SARS-CoV-2 variants altering the infectivity profile depends on levels of transmission in the community, and this dependence is used to infer Alpha and Delta variants infectivity profiles.
    1. Genetics and Genomics
    2. Medicine

    A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes

    Xiaojing Chu, Anna WM Janssen ... Yang Li
    Deep immunophenotyping characterizes the genetic factors influencing immune functionality in patients with type 1 diabetes.
    1. Neuroscience

    Self-organization of in vitro neuronal assemblies drives to complex network topology

    Priscila C Antonello, Thomas F Varley ... Jean Faber
    Effectively connected neurons self-organize forming networks with a small-world architecture composed of modules, with most likely few and nearby neurons, integrated by more topologically important and high firing rate neurons.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes

    Edhriz Siraliev-Perez, Jordan TB Stariha ... John Sondek
    PLC-γ isozymes are activated by a combination of receptor engagement and membrane proximity.
    1. Neuroscience

    Distinct representation of cue-outcome association by D1 and D2 neurons in the ventral striatum’s olfactory tubercle

    Nuné Martiros, Vikrant Kapoor ... Venkatesh N Murthy
    Real-time imaging of neural activity in behaving mice reveals that the two canonical types of neurons in the olfactory tubercle carry distinct information about learned odor cues, with D1 neurons representing stimulus valence and D2 neurons mainly representing stimulus identity.
    1. Neuroscience

    Multiple timescales of sensory-evidence accumulation across the dorsal cortex

    Lucas Pinto, David W Tank, Carlos D Brody
    Sensory-evidence accumulation is a distributed cortical computation, but frontal cortical areas contribute to accumulation on longer timescales than posterior cortical areas.