Browse our Research Articles

Page 412 of 1,393
    1. Cell Biology
    2. Immunology and Inflammation

    Tongue immune compartment analysis reveals spatial macrophage heterogeneity

    Ekaterini Maria Lyras, Karin Zimmermann ... Alexander Mildner
    The tongue is a unique barrier organ, which is constantly exposed to environmental pathogens, and therefore is expected to host an immune cell network ensuring local immune defence, which we characterised during development, health, and disease.
    1. Cell Biology

    Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami

    Shimaa A Abdellatef, Hisashi Tadakuma ... Keiko Hirose
    A pair of microtubules, ensembles of oppositely oriented axonemal dyneins, and inter-microtubule crosslinkers are the minimum components needed for oscillation and repetitive bending motions.
    1. Developmental Biology
    2. Neuroscience

    Cd59 and inflammation regulate Schwann cell development

    Ashtyn T Wiltbank, Emma R Steinson ... Sarah Kucenas
    Cd59 and developmental inflammation are key players in myelinating glial cell development, highlighting the collaboration between glia and the innate immune system to ensure normal neural development.
    1. Neuroscience

    Prefrontal cortex supports speech perception in listeners with cochlear implants

    Arefeh Sherafati, Noel Dwyer ... Jonathan E Peelle
    The use of high-density optical brain imaging in listeners with cochlear implants shows increased activity in frontal cortex during speech perception compared to those with normal hearing.
    1. Neuroscience

    Sleep-dependent upscaled excitability, saturated neuroplasticity, and modulated cognition in the human brain

    Mohammad Ali Salehinejad, Elham Ghanavati ... Michael A Nitsche
    The sleep-deprived brain in humans undergoes upscaled intracortical excitability which diminishes induction of LTP-like plasticity via transcranial electrical stimulation while converting the LTD-like to LTP-like plasticity and these physiological changes couple with impaired learning, memory, and attention at behavioral level.
    1. Neuroscience

    Sparse genetically defined neurons refine the canonical role of periaqueductal gray columnar organization

    Mimi Q La-Vu, Ekayana Sethi ... Avishek Adhikari
    Molecular genetic identity is a vital but unexplored axis of functional organization in the brainstem periaqueductal gray.
    1. Microbiology and Infectious Disease

    Metabolic basis for the evolution of a common pathogenic Pseudomonas aeruginosa variant

    Dallas L Mould, Mirjana Stevanovic ... Deborah A Hogan
    Microbial variants that arise during chronic lung infections have an increased ability to use nutrients that are abundant in lung infections.
    1. Biochemistry and Chemical Biology

    The orphan ligand, activin C, signals through activin receptor-like kinase 7

    Erich J Goebel, Luisina Ongaro ... Thomas B Thompson
    Activin class member, activin C, is a canonical TGFβ family member that signals through the type I receptor, action receptor-like kinase 7 and is resistant to follistatin antagonism.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes

    Laura M Doherty, Caitlin E Mills ... Peter K Sorger
    The integration of experimental and data mining approaches provides novel insights into deubiquitinating enzymes individually and as a gene family.
    1. Computational and Systems Biology

    Recurrent neural networks enable design of multifunctional synthetic human gut microbiome dynamics

    Mayank Baranwal, Ryan L Clark ... Ophelia S Venturelli
    Recurrent neural network models enable prediction and design of health-relevant metabolite dynamics in synthetic human gut communities.