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Pathological TNF-α-producing B cells are involved in the pathological process of polycystic ovary syndrome, and metformin inhibits mTOR phosphorylation, affects metabolic reprogramming, and further inhibits TNF-α expression in pathological B cells.

Distinct surfaces of an interbacterial competition cell wall toxin mediate interactions with different cellular binding partners, resulting in an inherent evolutionary trade-off across the toxin superfamily.

A novel strategy to create genetic mosaics in zebrafish for cell type-specific analysis of gene function that can be applied to any gene of interest.

Fewer neurons and more glia than previously predicted plus substantial differences between males and females are revealed when entire intact Drosophila larval central nervous systems are quantified using a synthesis of genetic, imaging, and computation technologies.

Internalization of apoptotic SARS-CoV-2 infected cells leads to proinflammatory macrophage activation and reduction in macrophage capacity to perform further efferocytosis.

Morphogenetic forces from tissue invagination orient cell division through a previously undescribed mechanism of force-dependent LGN/Pins polarization.

Models of malaria and treatment dynamics were combined with emulator-based global sensitivity analysis to elucidate the interplay between drug, biology, and epidemiological factors on the evolution of resistance to malaria treatments, including artemisinin.

Historical analysis of nearly half-a-million articles from the Journal of the American Medical Association and the New England Journal of Medicine since their inception frames the shifting scientific, material, ethical, and epistemic underpinnings of medicine over time, including today.

Sigma oscillations have a dual role in motor memory consolidation depending on their temporal coordination with slow waves during post-learning sleep.

The areas of the cerebral cortex that are necessary for mice to perform goal-directed navigation differ depending on previous experience in cognitively challenging tasks.