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Laboratory-based methods are presented that produce filamentous tau aggregates with the same structures as those observed in neurodegenerative disease.

Centriole rotational asymmetry, a structural property necessary for cytoskeletal organization in unicellular eukaryotes, is broadly conserved in the centrioles of human cells.

Proteins for bacterial flagella biogenesis contain two discrete export signals, recognised sequentially by the flagellar Type III Secretion System to facilitate initial docking and subsequent opening of the export gate.

A specific neuronal pathway within the auditory system represents information about the statistical prediction and error for incoming sounds, thereby contributing to efficient representation of complex sounds and sound streams in the brain.

The fossil record of abdominal modifications in male scorpionflies documents a relatively late evolution of oppressive behaviour toward a female during mating and suggest degree of sexual coercion greater in Eocene than in any other known scorpionfly, extinct or extant.

Noise-averaging cooperation (NAC) is a novel theory for the emergence of microbial cross-feeding by which noisy intracellular metabolism can promote cooperation and cross-feeding among cells.

Mucosal-associated invariant T cells, an emerging member of the innate-like T cells abundant in humans bridging the innate and the adaptive immunity, could be exploited as a novel tool for cancer immunotherapy through cell reprogramming.

Based on 3D visualization of fluorescently labeled cytoskeletal networks, an imaging platform is provided, which allows 3D network reconstruction, immersive visualization and quantification of local network properties serving as blueprints for functional modeling.

A bulk barcoded quantitative trait locus approach increases the power and resolution of genotype-phenotype mapping in yeast, revealing that the genetic architecture of 18 complex traits is highly polygenic, and is characterized by widespread epistatic interactions and pleiotropic effects.

Elaborate dendritic branch patterns lead to a local and branch-specific reduction in impedance, which attenuates back-propagating action potentials and limits voltage-gated calcium influx.