Marissa Jeme Andersen, ChunKi Fong ... Ana L Flores-Mireles
The use of liquid-infused catheters results in significant reduction of bladder and catheter colonization, systemic dissemination, and bladder inflammation in a clinically relevant mouse model of CAUTI by targeting host-protein deposition on the urinary catheter.
Intracellular protein gradients, which are formed by the combined action of cytoplasmic diffusion and cortical transport toward the cell pole, are solely determined by cell shape.
In order to homeostatically regulate many (n) properties at the same time, neurons must coadjust many (n + 1) ion channels with the appropriate ratios, which can lead to ion channel correlations and increased risk of regulation failure.
Identification of a heparan sulfate proteoglycan with a dedicated function in unconventional protein secretion reveals an intimate relationship between fibroblast growth factor 2 and Glypican-1 in cancer biology.
Luisa Maria Jaimes-Nino, Jürgen Heinze, Jan Oettler
Lifelong continuous reproduction, late-life investment into female sexuals, a short phase of senescence, and reproductive death characterize the life history of Cardiocondyla obscurior ant queens.
Actin-related protein 5 antagonizes the interaction of Pbx/Meis with myogenic regulatory factors such as MyoD and MyoG, which is involved in the recruitment of the BRG1-based switch/sucrose nonfermentable chromatin remodeling complex required for myogenic gene activation.
David W Hawman, Kimberly Meade-White ... Jesse H Erasmus
A replicating RNA vaccine platform generated significant immunity against SARS-CoV2 in mice and hamsters, and can be updated to target variants of concern.
Dynamic interactions of core clock molecules are quantitively measured and mathematically modelled to reveal the hidden role of PER:CRY complexes in enhancing the mobility of CLOCK:BMAL1 to move to new DNA sites.