Browse our Research Articles

Factoring out nucleotide-level mutation biases from antibody language models dramatically improves prediction of functional mutation effects while reducing computational cost by orders of magnitude.

Genomic neighborhood signatures delineate catalytic versus putative regulatory CODH clades, establishing a framework for predicting enzyme functionality and guiding discovery of biocatalysts for CO₂ reduction.

Peptidoglycan recycling is essential for proper cell growth and intrinsic ampicillin resistance in Caulobacter crescentus, highlighting PG recycling enzymes as potential antibacterial targets.

A fully automated 3D tracking framework reveals that sex and familiarity strongly shape natural social gaze dynamics in freely interacting marmosets.

Dysregulated exocytosis of bis(monoacylglycerol)phosphate (BMP)-enriched extracellular vesicles driven by pathogenic LRRK2 activity supports elevated urinary BMP levels and its use as a biomarker for Parkinson's disease.

A hierarchical framework integrating artificial intelligence with chemical principles enables the conversion of fragile α-helices into ultrastable protein scaffolds.

A specialized window-of-implantation endometrial assembloid enables investigation of human endometrial receptivity and maternal-fetal interaction.

Adolescents value reciprocity less than adults, limiting cooperation despite intact learning about others’ behavior.

Mycobacterium tuberculosis deploys nucleomodulins to suppress COMPASS-dependent H3K4 methylation, dampening pro-inflammatory gene expression to enhance intracellular survival and uncovering an epigenetic immune-evasion strategy.

Psilocin induces a durable neuroplastic state in human cortical neurons by enhancing BDNF signaling, neurite complexity, synaptogenesis, and synaptic network activity through 5-HT2A receptor-dependent mechanisms.