Browse our Research Articles

Page 5 of 1,485
    1. Developmental Biology

    Drosophila ryanodine receptor gene triggers functional and developmental muscle properties and could be used to assess the impact of human RYR1 mutations

    Monika Zmojdzian, Teresa Jagla ... Catherine Sarret
    The Drosophila ryanodine receptor plays a conserved role in setting functional and structural muscle properties, regulates embryonic muscle development and could be used to assess the impact of human RYR1 mutations.
    1. Neuroscience

    Dissociable neural substrates of integration and segregation in exogenous attention

    Yujie Chen, Ai-Su Li ... Yang Zhang
    Dissociable neural signatures of integration and segregation provide the first direct neuroimaging evidence for the integration-segregation theory of exogenous attention.
    1. Neuroscience

    An altered cell-specific subcellular distribution of translesion synthesis DNA polymerase kappa (POLK) in aging mouse neurons

    Mofida Abdelmageed, Premkumar Palanisamy ... Anirban Paul
    Progressive DNA polymerase kappa relocalization in aging neurons associates with increased DNA damage and identifies a novel cell type- and activity-dependent role in neuronal genome maintenance.
    1. Neuroscience

    Locus coeruleus modulation of prefrontal dynamics during attentional switching in mice

    Marco Nigro, Lucas Silva Tortorelli ... Hongdian Yang
    Inhibiting locus coeruleus input to the medial prefrontal cortex in mice impaired task performance, affected the tuning of single cortical neurons and disrupted population dynamics and encoding capacity during attentional switching.
    1. Neuroscience

    Characterisation of cold-selective lamina I spinal projection neurons in the mouse

    Aimi N Razlan, Wenhui Ma ... Junichi Hachisuka
    Lamina I projection neurons that respond selectively to skin cooling receive monosynaptic input from Trpm8-expressing primary afferents and innervate brain regions involved in perception of cold and cold defence mechanisms.
    1. Neuroscience

    A context-free model of savings in motor learning

    Mahdiyar Shahbazi, Olivier Codol ... Paul L Gribble
    Recurrent neural network models trained on a novel motor skill exhibit a persistent shift in preparatory activity that enables faster relearning, without cognitive or contextual cues.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Physiological febrile heat stress increases cytoadhesion through increased protein trafficking of Plasmodium falciparum surface proteins into the red blood cell

    David Jones, Hugo Belda ... Moritz Treeck
    Fever, often seen as protective, accelerates protein export to surfaces of malaria-infected RBCs, increasing adhesion linked to disease severity.
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    1. Neuroscience

    Cortical motor activity modulates respiration and reduces apnoea in neonates

    Coen S Zandvoort, Fatima Usman ... Caroline Hartley
    Communication between the cortex and respiration, known as cortico-respiratory coupling, occurs in newborn infants and relates to apnoea rate.
    1. Neuroscience

    Endogenous corazonin signaling modulates the post-mating switch in behavior and physiology in females of the brown planthopper and Drosophila

    Ning Zhang, Shao-Cong Su ... Shun-Fan Wu
    Endogenous corazonin signaling is a conserved female-driven regulator of the post-mating response in insects.
    1. Immunology and Inflammation

    HIV-1 envelope glycoprotein modulates CXCR4 clustering and dynamics on the T cell membrane

    Adriana Quijada-Freire, César A Santiago ... Mario Mellado
    HIV-1 remodels the spatial organization of its co-receptor, CXCR4, on T cell membranes, showing that viral entry requires receptor clustering rather than simple receptor binding.