Browse our Research Articles

GTPases could be drivers of liver fibrosis in MASLD and potential future therapeutic targets.

Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor immunity.

Superoxide dismutases, particularly Sod1, differentially tune redox signaling of germline and cyst stem cells, enabling their self-renewal and differentiation, thereby maintaining Drosophila testicular stem cell homeostasis.

NAT10-mediated mRNA acetylation links neural activity to local protein synthesis at synapses, influencing memory consolidation.

Topographically distributed plCoA populations direct innate olfactory responses by signaling to divergent valence-specific targets, linking upstream olfactory identity to downstream valence behaviors, through a population code.

Inactivation of beta 1,4-galactosyltransferase 1 leads to enhanced T-cell receptor activation and CD8⁺ T-cell function by affecting the galactosylation of T-cell receptor and CD8.

Competition between Quaking and SF1 for a subset of ACUAA intron branch sites influences alternative splicing in different tissues and organisms.

Studying the reproductive life history of an acoel reveals that a body-size-dependent program regulates organ growth and regeneration dynamics and discovers a novel form of egg-laying behavior.

Unique extracellular vesicle microRNA signatures resulting from G protein-coupled receptor activation indicate distinct downstream signaling and functional networks by receptor, with implications for developing new drugs and understanding their long-term and off-target effects.

The discovery of the earliest direct evidence of systematic proboscidean butchery at Olduvai Gorge demonstrates that by 1.8 Ma early hominins had strategically integrated megafaunal exploitation into their subsistence systems.