Pedro A Perez, Chung-Chih Liu ... Supriya Srinivasan
NK2R is a molecular switch linking tachykinin signaling to intestinal lipid handling, mucosal inflammation and gut microbiota, positioning NK2R-targeted peptide therapeutics for cardiometabolic and inflammatory bowel diseases.
A type VI secretion system transferred between gut bacteria via a mobile genetic element stabilizes its native host strain, but yields only transient benefits in a new species.
Hugo T Chow-Wing-Bom, Matteo Lisi ... Tessa M Dekker
Model‑based fMRI contrast‑sensitivity mapping provides a fixation‑tolerant, large‑field measure of cortical visual function that sensitively detects, localizes, and tracks visual field loss and recovery.
Integrating genome-wide maps of chromatin accessibility and sequence conservation provides an accessible low-cost approach for identifying cis-regulatory elements in large genomes, validated in the emerging model Parhyale.
The anterior cingulate cortex selectively reorganizes communication with superficial CA1 neurons during sharp-wave ripples to balance memory consolidation following new learning.
Blair RK Shevlin, Loren Gianini ... Laura A Berner
In bulimia nervosa, negative affect exaggerates a taste-before-health bias in food decision-making, and this bias is associated with more frequent out-of-control eating.
Beyond genotype × environment interactions, which can be shared and identical across individuals, learning from uniquely individual experiences further defines and diversifies individual behaviour.