Browse our Research Articles

Titin-associated muscle ankyrin repeat proteins limit stretch-induced longitudinal muscle hypertrophy and link titin mechanosensing to mTOR signaling.

Fundamental distinctions in the extracellular signatures of active-dendritic chemical and electrical synapses necessitate a revision of conventional interpretations of local field potentials centered on chemical synapses.

A time-dependent genetic interaction between the µ opioid receptor and genes drives early morphine responses in mice, highlighting pathways linked to human substance use disorder.

Gaze patterns during value-based choice may reflect post-decision processes rather than a direct causal influence of attention on preference formation.

MgIG directly targets HSD11B1 to alleviate alcohol-associated liver disease by suppressing the HSD11B1–SREBP2–IDI1 pathway, thereby reducing hepatic steatosis, inflammation, and apoptosis.

Cholecystokinin release from CA3 inputs to CA1 links local excitatory circuitry to hippocampal plasticity and spatial memory.

TNF-driven metabolic reprogramming enhances glucose utilization in monocytes through inducible nitric oxide synthase (iNOS) and hypoxia-inducible factor 1α (HIF-1α), promoting parasite control and host resistance during Plasmodium infection.

The brain computes rapidly and reliably using brief electrical impulses and likely exploits internal memory in nerve cells to achieve this more efficiently than existing computing hardware and neural networks.

Type I and type II inhibitors differentially affect LRRK2 filament formation around microtubules, revealing an important consideration for Parkinson’s disease drug development.

Flexible evidence accumulation in dynamic environments relies on multiple mechanisms, including context-dependent modulations of sensory adaptation and pupil-linked arousal.