Elise LV Malavasi, Aniket Ghosh ... Peter J Brophy
Dynamic early clusters of nodal proteins in peripheral nerves represent a neurofascin-dependent developmental stage of node assembly during myelination that precedes heminode formation.
DNA lesions formed by alkylating agents trigger double-strand breaks, in the absence of replication, by the action of MMR and BER at nearby O-alkyl and N-alkyl adducts, respectively.
Pedro Ortega, José Antonio Mérida-Cerro ... Andrés Aguilera
Genetic and physical analyses reveal that DNA-RNA hybrids form fortuitously at DNA double-strand breaks during transcription and need removal to allow repair by homologous recombination.
Aniruddha Chattaraj, Michael L Blinov, Leslie M Loew
The solubility product, a thermodynamic concept classically applied to poorly soluble ionic solutes, can rationalize the concentration dependence for liquid-liquid phase separation of multicomponent multivalent molecules.
Perceptual decisions are influenced by preceding choices to a larger extent in individuals with autism spectrum disorder, such that they demonstrate a greater consistency bias.
Functional and molecular analyses of two distinct skeletal stem cell populations establish the important role of stem cell diversity that provides a framework for novel investigations into skeletal biology.
Megan Culler Freeman, Alexandra I Wells ... Carolyn B Coyne
Parallel studies in primary human airway cells and stem cell-derived enteroids show that Enterovirus D-68 differentially infects and induces innate immune signaling in the respiratory and intestinal epithelium.