Browse our Research Articles

Page 606 of 1,424
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development

    Lucie Zilova, Venera Weinhardt ... Joachim Wittbrodt
    Fish-derived pluripotent cells instinctively form retinal tissue recapitulating key steps of early eye development.
    1. Neuroscience

    Increased theta/alpha synchrony in the habenula-prefrontal network with negative emotional stimuli in human patients

    Yongzhi Huang, Bomin Sun ... Huiling Tan
    Increased theta/alpha band activities within the habenula area and the prefrontal cortex, as well as the increased synchrony between the two structures in the same frequency band can serve as an indicator for negative emotions in humans.
    1. Cell Biology
    2. Physics of Living Systems

    Mechanical stretch scales centriole number to apical area via Piezo1 in multiciliated cells

    Saurabh Kulkarni, Jonathan Marquez ... Mustafa K Khokha
    Embryonic and mechanical manipulations of Xenopus multiciliated epithelium reveals that cell non-autonomous tensile forces generated by embryonic elongation calibrate cilia number in multiciliated cells via a mechanosensitive ion channel, Piezo1.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Injection with Toxoplasma gondii protein affects neuron health and survival

    Oscar A Mendez, Emiliano Flores Machado ... Anita A Koshy
    Multi-level profiling of Toxoplasma gondii-injected neurons identifies brain regions and neuron subtype predilections as well as the effect of Toxoplasma interactions on neuron physiology and health.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain

    Michael Sheinman, Ksenia Arkhipova ... Florian Massip
    Horizontal gene transfer between distantly related bacterial species is frequent and widespread and can be efficiently identified using alignment-free methods.
    1. Neuroscience

    De novo learning versus adaptation of continuous control in a manual tracking task

    Christopher S Yang, Noah J Cowan, Adrian M Haith
    Humans can rapidly build a new controller when learning continuous movement tasks and can flexibly integrate this process with adaptation of an existing controller.
    1. Neuroscience

    A bidirectional corticoamygdala circuit for the encoding and retrieval of detailed reward memories

    Ana C Sias, Ashleigh K Morse ... Kate M Wassum
    The bidirectional orbitofrontal cortex-basolateral amygdala circuit helps us to learn the details of predicted rewarding events and then to use that information to make good reward pursuit decisions.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    A phase transition enhances the catalytic activity of SARM1, an NAD+ glycohydrolase involved in neurodegeneration

    Heather S Loring, Victoria L Czech ... Paul R Thompson
    The catalytic activity of SARM1, a key promoter of neuronal degeneration, is activated by >2000-fold by a phase transition.
    1. Cell Biology

    A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics

    Elizabeth M Steenkiste, Jason D Berndt ... Jonathan A Cooper
    Epithelial cells coordinate integrin signaling with protrusion via a two-protein module, with one protein defining localization and downstream signaling, the other serving as a phosphorylation switch and providing negative feedback.
    1. Computational and Systems Biology
    2. Developmental Biology

    The pattern of nodal morphogen signaling is shaped by co-receptor expression

    Nathan D Lord, Adam N Carte ... Alexander F Schier
    Ligand capture by cell surface receptor complexes sets the shape of the Nodal signaling pattern in zebrafish.