Marina E Wosniack, Jan H Kirchner ... Julijana Gjorgjieva
To generate stable and robust connectivity refinements, the amplitude of spontaneous activity events in the developing visual cortex adapts to the recent history of cortical activation.
NMDAR receptors act in regulating axon guidance of somatosensory callosal projections in early postnatal life and the expression of EPHB2 receptors in target cells.
Toshihide W Yoshioka, Takahiro Doi ... Ichiro Fujita
Visual area MT signals binocular disparity quickly and robustly, whereas area V4 or its upstream area transforms the nature of the signals to derive a more sophisticated depth representation.
The c-terminus of PI3K plays a key role in regulating kinase activity, with c-terminal disease-linked mutations leading to either activation or inhibition, which reveal a path to specific inhibitors.
Spatial restriction of GPCR signaling at nascent synapses by adhesion complexes drives excitatory synapse formation and specificity in the hippocampus.
A comparative analysis of human and chimpanzee polyadenylation site usage establishes alternative polyadenylation as another key mechanism underlying the genetic regulation of transcript and protein expression levels in primates.