Yulia Bereshpolova, Xiaojuan Hei ... Harvey A Swadlow
In the visual system, three rules guide the thalamocortical connectivity of cortical fast-spike interneurons and are key to understand the potent and broadly tuned feed-forward inhibition that they generate.
María Crespo, Barbara Gonzalez-Teran ... Guadalupe Sabio
Circadian neutrophil infiltration in the liver modulates liver clock-gene expression and daily hepatic metabolism through the secretion of elastase and activation of JNK-FGF21-Bmal1 axis in the hepatocyte.
Skin cells in zebrafish use sodium chloride-dependent electrical gradients to sense tissue injury and guide migration in the appropriate direction to close the wound.
Isaac J Jensen, Samantha N Jensen ... Vladimir P Badovinac
Sepsis-induced numerical loss of naive autoantigen-specific CD4 T cells reduces host capacity to develop autoimmune immune disease, thereby demonstrating an intriguing relationship between infection and autoimmune disease.
Astrocyte microdomain calcium transients are mediated by TrpML, stimulated by ROS and tyramine, and mediate astrocyte–tracheal interactions in CNS gas exchange.
Damilola Pinheiro, Marie-Anne Mawhin ... Kevin J Woollard
In-silico modeling of gene and protein emergence reveals how colony-stimulating factors contributed to the evolution and functional adaptions observed in mammalian neutrophils.
Upendo Lupanga, Rachel Röhrich ... Karin Schumacher
Analysis of the Arabidopsis V-ATPase reveals convergent evolution of differential targeting as well as redundancy of the endosomal and vacuolar isoforms during vegetative development.
Spatially and temporally patterned activation of the small GTPase Rho1 indicates that ventral-specific factors contribute to cell- and tissue-level behaviors during ventral furrow formation, the first step in Drosophila gastrulation.