Browse our Research Articles

Page 689 of 1,408
    1. Cell Biology
    2. Developmental Biology

    AKAP6 orchestrates the nuclear envelope microtubule-organizing center by linking golgi and nucleus via AKAP9

    Silvia Vergarajauregui, Robert Becker ... Felix B Engel
    AKAP6 is a site-specific adaptor required and sufficient to anchor centrosomal proteins and golgi to the nuclear envelope and establishes a non-centrosomal microtubule organization center (ncMTOC).
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis

    Alisa Atkins, Michelle J Xu ... Philip W Jordan
    The structural maintenance of chromosomes complex, SMC5/6, is crucial for brain development and function as it ensures proficient DNA replication in neural progenitor cells prior to chromosome segregation.
    1. Neuroscience

    Chimpanzee brain morphometry utilizing standardized MRI preprocessing and macroanatomical annotations

    Sam Vickery, William D Hopkins ... Felix Hoffstaedter
    Openly available structural imaging processing pipeline for chimpanzees including registration templates and macro-anatomical parcellation shows human-like cerebral aging and medial hemispheric organization.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Bedrock radioactivity influences the rate and spectrum of mutation

    Nathanaëlle Saclier, Patrick Chardon ... Christophe J Douady
    Subterranean isopods endemic to regions with large igneous rock formations have a higher mutation rate and display an excess of mutations that are typical of an oxidative stress.
    1. Neuroscience

    Visual attention modulates the integration of goal-relevant evidence and not value

    Pradyumna Sepulveda, Marius Usher ... Benedetto De Martino
    Visual attention modulates the integration of the evidence that is most useful for achieving a goal in both perceptual and value-based decisions.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Plasma proteomic biomarker signature of age predicts health and life span

    Toshiko Tanaka, Nathan Basisty ... Luigi Ferrucci
    Analysis of proteomic data identified protein biomarkers of aging, mortality and aging-related diseases, supporting their use to monitor aging trajectories and identify individuals at higher risk of disease.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

    Yiska Weisblum, Fabian Schmidt ... Paul D Bieniasz
    SARS-CoV-2 spike variants that resist neutralization by therapeutic antibodies or convalescent plasma can be generated in the laboratory and exist at low frequency in natural populations.
    1. Neuroscience

    An interactive meta-analysis of MRI biomarkers of myelin

    Matteo Mancini, Agah Karakuzu ... Nikola Stikov
    Most MRI-based myelin biomarkers are not statistically different regarding their relationship with histology.
    1. Microbiology and Infectious Disease

    The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion

    Christine R Collins, Fiona Hackett ... Michael J Blackman
    Genetic analysis identifies an enzyme of the malaria parasite that is required to seal its host red blood cell membrane upon invasion, a key requirement of this important intracellular pathogen.
    1. Microbiology and Infectious Disease

    Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization

    Soner Yildiz, João P Pereira Bonifacio Lopes ... Mirco Schmolke
    A respiratory tissue-associated commensal Lactobacillus strain confers colonization resistance to Streptococcus pneumoniae, when applied therapeutically in a post influenza virus super-infection model.