Bjoern Gaertner, Sebastiaan van Heesch ... Maike Sander
Ribosome profiling and loss-of-function during human ESC pancreatic differentiation reveal abundant lncRNA translation and an essential role for translated LINC00261 in beta cell differentiation, likely through a trans-regulatory, microprotein-independent mechanism.
Kazuki Shiotani, Yuta Tanisumi ... Hiroyuki Manabe
Individual neurons of ventral tenia tecta which is a part of olfactory cortex tune to specific time windows in the behavioral context during odor-guided goal-directed behaviors.
Md Rakibul Hasan, Maarit Takatalo ... David PC Rice
RAB23 regulates calvarial bone and suture development both independently through, and by cross-talk between, Hedgehog and fibroblast growth factor signaling.
Nicolas Carraro, Xavier Richard ... Jan Roelof van der Meer
A new multistep hierarchical cascade controls activation of an integrative and conjugative element in a small subpopulation of cells in its bacterial host, yielding proficient DNA transferring cells.
In medaka fish, galanin-expressing neurons in the medial preoptic area occur nearly exclusively in males and mediate androgen-dependent male–male aggressive chases.
Two evolutionary distant insect species share a common head direction circuit with subtle differences in neuronal morphologies that result in distinct circuit dynamics adapted to each species’ ecology.
Structure of the Mrp antiporter, an ancestor of respiratory complex I, suggests a mechanism of coupling between cation and proton translocation, applicable to a large family of related membrane proteins.
David M Curran, Alexandra Grote ... John Parkinson
A genome scale model of Brugia malayi metabolism illustrates a dynamic reliance on energy production pathways across its life cycle and identifies new drugs with experimentally supported anti-parasitic properties.
The brown planthopper has evolved a highly adaptive oviposition strategy by exploiting caterpillar-induced plant volatiles that provide safe havens for its offspring.
