Browse our Research Articles

A mouse model of retinal degeneration reveals a common mechanism for axonal degeneration and photoreceptor cell death and identifies SARM1 as a therapeutic candidate for retinopathies.

HemK NTD cotranslational folding starts within the ribosome exit tunnel upon N-terminal helix synthesis and proceeds sequentially through a series of intermediates becoming less dynamic as the nascent chain grows.

Cell cycle phase-specifically induced long non-coding RNAs regulate cell proliferation by modulating crucial cell signaling pathways.

Fully assembled DNA methylomes from phylogeographically diverse clinical Mycobacterium tuberculosis complex isolates reveals 'intercellular mosaic methylation' as a source of epigenetic diversity.

Glycosylation of flagellins with pseudaminic acid in the bacterial cytoplasm governed by an unknown type of modular glycosyltransferase harboring an N-terminal substrate binding domain and a C-terminal glycosyltransferase domain.

The Wtf4 antidote protein assembles with the Wtf4 poison protein and promotes the transportation of the assembled proteins to the vacuole for sequestration or destruction.

fMRI evidence for distinct hierarchical alterations in intrinsic neural timescales for different positive symptoms of schizophrenia support hierarchical perceptual-inference models of psychosis and suggest local increases in excitation-inhibition ratio.

Translational evidence indicates APOE2 benefits longevity independent of its protective effects on Alzheimer’s disease, which preserved activity and the metabolism of apoE protein and associated-lipids would be key to understanding.

Projections from the prelimbic prefrontal cortex targeting the ventral striatum or the basolateral amygdala bidirectionally regulate platform-mediated active avoidance in rats.

Cryo-electron tomography reveals the structure and arrangement of the VP40 matrix protein lattice that mediates the formation of Ebola and Marburg virus particles.