Browse our Research Articles

Page 857 of 1,383
    1. Epidemiology and Global Health

    Parental vaccination to reduce measles immunity gaps in Italy

    Valentina Marziano, Piero Poletti ... Stefano Merler
    Offering measles vaccination to parents who bring their children to receive any dose of measles vaccine can accelerate measles elimination in Italy.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes

    Nimisha Chaturvedi, Evguenia S Svarovskaia ... Jacques Fellay
    Integrated analysis of IFN-λ and HCV amino acid variation indicates the key role of host innate immunity in viral control.
    1. Cancer Biology

    FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

    Carlos J Diaz Osterman, Duygu Ozmadenci ... David D Schlaepfer
    Genomic gains in ovarian cancer can promote cisplatin resistance via a FAK, Wnt/beta-catenin and Myc signaling pathway supporting pluripotency genes and tumorspheres that can acquire FAK dependence for survival.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Correlated evolution between repertoire size and song plasticity predicts that sexual selection on song promotes open-ended learning

    Cristina M Robinson, Kate T Snyder, Nicole Creanza
    A longer birdsong-learning window evolves in response to sexual selection for song complexity and is associated with faster evolution of song performance characteristics.
    1. Developmental Biology

    MicroRNA-mediated control of developmental lymphangiogenesis

    Hyun Min Jung, Ciara T Hu ... Brant M Weinstein
    Lymphatic-enriched microRNA miR-204 is required for lymphatic development through its effects on the key lymphatic transcription factor NFATC1.
    1. Developmental Biology
    2. Neuroscience

    Retrograde Ret signaling controls sensory pioneer axon outgrowth

    Adam Tuttle, Catherine M Drerup ... Alex V Nechiporuk
    Long-range Ret receptor signaling promotes axon outgrowth and regulates growth cone dynamics in pioneer neurons by inducing transcriptional changes in Myosin-X expression.
    1. Neuroscience

    The readily-releasable pool dynamically regulates multivesicular release

    Jada H Vaden, Gokulakrishna Banumurthy ... Jacques I Wadiche
    The number of neurotransmitter vesicles released into the synaptic cleft is regulated by the size of the readily-releasable pool upstream of release probability.
    1. Computational and Systems Biology
    2. Neuroscience

    Statistical context dictates the relationship between feedback-related EEG signals and learning

    Matthew R Nassar, Rasmus Bruckner, Michael J Frank
    The P300, an electroencephalography (EEG) component known to be evoked by surprising events, predicts learning in a bidirectional manner that depends critically on the surrounding statistical context.
    1. Evolutionary Biology

    Coupling adaptive molecular evolution to phylodynamics using fitness-dependent birth-death models

    David A Rasmussen, Tanja Stadler
    A new model describes how adaptive molecular evolution shapes phylogenetic trees and can be used to estimate the fitness effects of mutations from phylogenies.
    1. Biochemistry and Chemical Biology

    Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb

    Joshua E Mayfield, Seema Irani ... Yan Zhang
    The phosphorylation of tyrosine in the heptad repeat of the C-terminal domain of the largest subunit of RNA polymerase II promotes Ser2 phosphorylation by P-TEFb for pausing release.