The overactivation of noradrenergic inputs to the amygdala during severe fear learning increases memory stability at the expense of lability, rendering the trace resistant to memory destabilization and reconsolidation.
Kateřina Benediktová, Jana Adámková ... Hynek Burda
Before returning home, and when using novel routes, dogs align along the north-south axis, presumably to bring the mental map into register with the magnetic compass.
Taste-dependent satiation, which induces proper cessation of feeding in mammals as well as insects, is weakened by sugar-diet-driven taste impairment in the fruit fly.
Vincenza Caolo, Marjolaine Debant ... David J Beech
Cell protease and cell fate decisions are regulated by a bone fide force-sensor, the Piezo1 channel, and by this means achieve integration with the mechanical environment.
Edward J Banigan, Aafke A van den Berg ... Leonid A Mirny
Seemingly contradictory findings of single-molecule and in vivo experiments on a major mechanism of chromosome organization are reconciled by computationally investigating mechanisms of loop extrusion that are consistent with both.
Kanella Prodromidou, Ioannis S Vlachos ... Rebecca Matsas
Primate-specific miR-934 mediates neurogenesis and downstream neuronal differentiation processes, modulating the expression of genes associated with the subplate, a region most prominent in primates, emerging during early cortical development.
Adaptations in protein synthesis and mRNA surveillance machinery enabled the malaria-causing parasite P. falciparum to efficiently and accurately translate long polyA nucleotide runs into long poly-lysine peptides.