An in-depth metagenomic analysis of possibly the most abundant and widespread microbial lineage in the surface ocean teases apart evolutionary processes that maintain its genomic heterogeneity and biogeography.
M Azim Ansari, Elihu Aranday-Cortes ... Vincent Pedergnana
Interferon lambda 4, a protein part of the innate immune response, drives major amino acids selection in patients chronically infected with hepatitis C virus.
Carlos J Diaz Osterman, Duygu Ozmadenci ... David D Schlaepfer
Genomic gains in ovarian cancer can promote cisplatin resistance via a FAK, Wnt/beta-catenin and Myc signaling pathway supporting pluripotency genes and tumorspheres that can acquire FAK dependence for survival.
Cristina M Robinson, Kate T Snyder, Nicole Creanza
A longer birdsong-learning window evolves in response to sexual selection for song complexity and is associated with faster evolution of song performance characteristics.
Adam Tuttle, Catherine M Drerup ... Alex V Nechiporuk
Long-range Ret receptor signaling promotes axon outgrowth and regulates growth cone dynamics in pioneer neurons by inducing transcriptional changes in Myosin-X expression.
Jada H Vaden, Gokulakrishna Banumurthy ... Jacques I Wadiche
The number of neurotransmitter vesicles released into the synaptic cleft is regulated by the size of the readily-releasable pool upstream of release probability.