Browse our Research Articles

Page 872 of 1,398
    1. Developmental Biology
    2. Evolutionary Biology

    Hemimetabolous insects elucidate the origin of sexual development via alternative splicing

    Judith Wexler, Emily Kay Delaney ... Artyom Kopp
    Sexual differentiation controlled by sex-specific mRNA splicing evolved in a step-wise manner in insects.
    1. Genetics and Genomics

    Single-amino acid variants reveal evolutionary processes that shape the biogeography of a global SAR11 subclade

    Tom O Delmont, Evan Kiefl ... A Murat Eren
    An in-depth metagenomic analysis of possibly the most abundant and widespread microbial lineage in the surface ocean teases apart evolutionary processes that maintain its genomic heterogeneity and biogeography.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Interferon lambda 4 impacts the genetic diversity of hepatitis C virus

    M Azim Ansari, Elihu Aranday-Cortes ... Vincent Pedergnana
    Interferon lambda 4, a protein part of the innate immune response, drives major amino acids selection in patients chronically infected with hepatitis C virus.
    1. Epidemiology and Global Health

    Parental vaccination to reduce measles immunity gaps in Italy

    Valentina Marziano, Piero Poletti ... Stefano Merler
    Offering measles vaccination to parents who bring their children to receive any dose of measles vaccine can accelerate measles elimination in Italy.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes

    Nimisha Chaturvedi, Evguenia S Svarovskaia ... Jacques Fellay
    Integrated analysis of IFN-λ and HCV amino acid variation indicates the key role of host innate immunity in viral control.
    1. Cancer Biology

    FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

    Carlos J Diaz Osterman, Duygu Ozmadenci ... David D Schlaepfer
    Genomic gains in ovarian cancer can promote cisplatin resistance via a FAK, Wnt/beta-catenin and Myc signaling pathway supporting pluripotency genes and tumorspheres that can acquire FAK dependence for survival.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Correlated evolution between repertoire size and song plasticity predicts that sexual selection on song promotes open-ended learning

    Cristina M Robinson, Kate T Snyder, Nicole Creanza
    A longer birdsong-learning window evolves in response to sexual selection for song complexity and is associated with faster evolution of song performance characteristics.
    1. Developmental Biology

    MicroRNA-mediated control of developmental lymphangiogenesis

    Hyun Min Jung, Ciara T Hu ... Brant M Weinstein
    Lymphatic-enriched microRNA miR-204 is required for lymphatic development through its effects on the key lymphatic transcription factor NFATC1.
    1. Developmental Biology
    2. Neuroscience

    Retrograde Ret signaling controls sensory pioneer axon outgrowth

    Adam Tuttle, Catherine M Drerup ... Alex V Nechiporuk
    Long-range Ret receptor signaling promotes axon outgrowth and regulates growth cone dynamics in pioneer neurons by inducing transcriptional changes in Myosin-X expression.
    1. Neuroscience

    The readily-releasable pool dynamically regulates multivesicular release

    Jada H Vaden, Gokulakrishna Banumurthy ... Jacques I Wadiche
    The number of neurotransmitter vesicles released into the synaptic cleft is regulated by the size of the readily-releasable pool upstream of release probability.