A systematic assessment of previously proposed fMRI metrics of motor sequence learning reveals widespread activity reductions and subtle multivariate pattern changes outside of primary motor cortex.
Sarah Jacquelyn Smith, Lance A Davidson, Mark Rebeiz
A new morphological structure evolved through extreme changes in cell height requires novel connections to an extracellular matrix network, which predates the origin of structure.
Targeting the differentiation regulators and/or AMPs of keratinocytes, rather than targeting immune cells, may be an alternative approach for topical anti-psoriatic treatment, an area with high need for new drugs.
Extensive molecular profiling shows how loss of highly similar, paralogous ribosomal proteins lead to distinct phenotypic outputs, through translational control of specific mRNAs.
Maternal spindle transfer is a feasible approach to enhance embryonic developmental of compromised oocytes, which can represent a new strategy for patients with forms of infertility refractory to current treatments.
Robust fear learning deficits and decreased tonic activity of NAc cholinergic interneurons caused by depletion of MeCP2 could be attributed to an elevation in α2-containing GABAA receptors.
Calcium release from the endoplasmic reticulum through the IP3 receptor ion channel is strongly regulated by a calcium-binding protein in the lumen of the endoplasmic reticulum.
Macrophage Bmal1 controls the timing of the glycolytic to oxidative metabolism transition that dictates the extent of Hif-1a activation and the associated inflammatory response.