Browse our Research Articles

Page 879 of 1,395
    1. Neuroscience

    Distinct subdivisions of human medial parietal cortex support recollection of people and places

    Edward H Silson, Adam Steel ... Chris I Baker
    Recalling either specific people or places from memory selectively recruits separate regions of human medial parietal cortex in a pattern reminiscent of how visual cortex represents these visual categories.
    1. Ecology
    2. Evolutionary Biology

    Variable opportunities for outcrossing result in hotspots of novel genetic variation in a pathogen metapopulation

    Anna-Liisa Laine, Benoit Barrès ... Jukka P Siren
    In natural pathogen populations opportunities for sexual outcrossing vary, leading to spatial variation in genetic diversity and between-season survival.
    1. Cancer Biology
    2. Developmental Biology

    The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

    Jean-Philippe Parvy, Yachuan Yu ... Julia B Cordero
    Natural activity of the antimicrobial peptide Defensin includes execution of tumour cell death by tumour necrosis factor in Drosophila.
    1. Developmental Biology
    2. Neuroscience

    Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA

    Cheng Yung Lin, Chia Lun Wu ... Huai Jen Tsai
    The amount of secreted Pgk1 is sharply decreased in Rtn4al/NogoA-overexpressed muscle cells, leading to various manifestations of neurodegenerative disease, including denervated neuromuscular junction and failed neurite outgrowth of motoneurons.
    1. Physics of Living Systems

    Cell-sized confinement controls generation and stability of a protein wave for spatiotemporal regulation in cells

    Shunshi Kohyama, Natsuhiko Yoshinaga ... Nobuhide Doi
    A cell-sized fully confined space significantly controls the emergence and stability of a protein wave, resulting in intracellular spatiotemporal regulation driven by a reaction-diffusion mechanism.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural insights into flagellar stator–rotor interactions

    Yunjie Chang, Ki Hwan Moon ... Jun Liu
    In situ structural analysis of bacterial flagellar motor in the Lyme disease spirochete reveals novel conformational change driven by proton motive force.
    1. Neuroscience

    Inter-individual differences in human brain structure and morphology link to variation in demographics and behavior

    Alberto Llera, Thomas Wolfers ... Christian F Beckmann
    Multi-modal structural data fusion questions the specificity of fMRI-behavior associations by providing strong evidence relating human brain structure to a wide range of behavioral measures previously associated to functional connectivity.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels

    Florian Ullrich, Sandy Blin ... Thomas J Jentsch
    TMEM206 proteins are identified as constituting the pore of the widely expressed acid-activated chloride channel PAORAC/ASOR, which is important in acid toxicity.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly

    Sudeep Banjade, Shaogeng Tang ... Scott D Emr
    ESCRT-III heteropolymers utilize non-specific lateral electrostatic interactions to recognize one another, which may enable the polymers to slide along one another and adapt to different curvatures.
    1. Developmental Biology

    Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate

    Dasan Mary Cibi, Masum M Mia ... Manvendra K Singh
    The identification of the splicing code and all the required components of alternative splicing will be crucial for a comprehensive understanding of this process in the neural crest cell biology.