Browse our Research Articles

Page 986 of 1,471
    1. Physics of Living Systems

    A multiphase theory for spreading microbial swarms and films

    Siddarth Srinivasan, C Nadir Kaplan, L Mahadevan
    A multiphase hydrodynamic theory reveals that the dynamics of colony expansion in microbial swarms and biofilms are limited by the constraints of water and nutrient availability.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency

    Maxim Greenberg, Aurélie Teissandier ... Deborah Bourc'his
    Three-dimensional chromatin architecture facilitates a promoter switch in order to ensure maintained expression of a gene involved in growth during embryonic stem cell differentiation.
    1. Neuroscience

    Anterior insular cortex plays a critical role in interoceptive attention

    Xingchao Wang, Qiong Wu ... Jin Fan
    Anterior insular cortex activity predicts how well we attend to our bodily signals, while lesions to this brain region disrupt this ability.
    1. Neuroscience

    Shank3 modulates sleep and expression of circadian transcription factors

    Ashley M Ingiosi, Hannah Schoch ... Lucia Peixoto
    Shank3, a high confidence autism gene candidate, may be a key component of the mechanisms underlying sleep problems in autism.
    1. Evolutionary Biology

    Evolution of empathetic moral evaluation

    Arunas L Radzvilavicius, Alexander J Stewart, Joshua B Plotkin
    Empathy can evolve and foster cooperation in a game-theoretic analysis of behavior.
    1. Neuroscience

    Selective attenuation of Ether-a-go-go related K+ currents by endogenous acetylcholine reduces spike-frequency adaptation and network correlation

    Edward D Cui, Ben W Strowbridge
    Acetylcholine, a common modulator in the brain, controls spike-frequency adaptation by specifically attenuating Ether-a-go-go related K+ currents, thereby explaining many cortical network statistical changes often observed in vivo.
    1. Neuroscience

    A cross-modality enhancement of defensive flight via parvalbumin neurons in zona incerta

    Xiyue Wang, Xiaolin Chou ... Huizhong W Tao
    Parvalbumin positive GABAergic neurons in the ventral zona incerta receive input from somatosensory cortex and enhance sound-induced flight behavior, which underlies a cross-modality facilitation of defensive behavior by somatosensory input.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Transitions in cell potency during early mouse development are driven by Notch

    Sergio Menchero, Isabel Rollan ... Miguel Manzanares
    The Notch signaling pathway drives transitions in differentiation capacities during the gradual loss of potency that occurs in the preimplantation mouse embryo before the onset of the first lineage decisions.
    1. Computational and Systems Biology
    2. Developmental Biology

    Retinal stem cells modulate proliferative parameters to coordinate post-embryonic morphogenesis in the eye of fish

    Erika Tsingos, Burkhard Höckendorf ... Joachim Wittbrodt
    3D niche topology imposes a spatially biased random stem cell loss, which is differentially fine-tuned in neural retina and retinal pigmented epithelium to regulate growth, shape, and cellular topology.
    1. Biochemistry and Chemical Biology

    Enterococcus faecium secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis

    Byungchul Kim, Yen-Chih Wang ... Howard C Hang
    Enterococci faecium encodes unique peptidoglycan composition and remodeling activity that activates host immunity.