Browse our Short Reports

Artificial RNA interference is a novel loss-of-function method for highly stringent target validation in oncology and beyond.

Application of museomics facilitates characterization of the contribution of historical factors to genetic diversity declines in Numenius shorebirds and highlights that extinction of ecosystem-engineering megafauna may have been detrimental for open-landscape species.

HIV-1 infection activates the human CARD8 inflammasome via innate immune recognition of HIV-1 viral protease activity.

Combination of primary brain culture and single-cell RNA sequencing in brain organoids identifies microglia as the main target of rubella virus infection.

Biallelic MAD2L1BP variants contribute to oocyte metaphase I arrest in women with primary infertility and p31^comet is required for human oocyte maturation.

A new perspective on the 50-year old mystery of why phages encode their own tRNAs.

Metabolomic analyses indicate that diet generalism may stem from a neutral metabolic response to different chemistries, rather than from an accumulation of specific adaptations.

MLL1-mediated H3K4 methylation is directly enhanced by cis-tail H3 acetylation, as shown through both in vitro and in vivo experiments.

In juvenile songbirds, neural sequences pre-exist tutor exposure, and the process of learning a new song may make use of existing neural sequences as a stable substrate for new behavioral changes.

Oscillations that co-occur in hippocampal CA1 during exploration in the rodent are shown to segregate according to exploratory and sleep states in the primate.